An Efficient One-Pot, Four-Component Synthesis of Pyrazolo[3,4-b]pyridines Catalyzed by Tetrapropylammonium Bromide (TPAB) in Water

Mahnaz Ezzati; Jabbar Khalafy; Ahmad Poursattar Marjani; Rolf H Prager

doi:10.1071/CH17642

An Efficient One-Pot, Four-Component Synthesis of Pyrazolo[3,4-b]pyridines Catalyzed by Tetrapropylammonium Bromide (TPAB) in Water

Mahnaz Ezzati, Jabbar Khalafy, Ahmad Poursattar Marjani, Rolf H Prager

College of Science and Engineering

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

A novel and one-pot pseudo-four-component reaction between a series of arylglyoxals, malononitrile, 3-methyl-1-phenyl-1H-pyrazol-5-amine, and acetone in the presence of tetrapropylammonium bromide (TPAB) has been developed to synthesize a series of new substituted pyrazolo[3,4-b]pyridines, using water as an environmentally friendly solvent, in high to excellent yields.

Original language	English
Pages (from-to)	435-441
Number of pages	7
Journal	Australian Journal of Chemistry
Volume	71
Issue number	6
Early online date	8 May 2018
DOIs	https://doi.org/10.1071/CH17642
Publication status	Published - Jun 2018

Keywords

Tetrapropylammonium bromide
One-pot
Arylglyoxals
Acetone
Solvent

Access to Document

10.1071/CH17642Licence: In Copyright

Cite this

@article{6ab4178b14d64c1391b53406cde1986b,

title = "An Efficient One-Pot, Four-Component Synthesis of Pyrazolo[3,4-b]pyridines Catalyzed by Tetrapropylammonium Bromide (TPAB) in Water",

abstract = "A novel and one-pot pseudo-four-component reaction between a series of arylglyoxals, malononitrile, 3-methyl-1-phenyl-1H-pyrazol-5-amine, and acetone in the presence of tetrapropylammonium bromide (TPAB) has been developed to synthesize a series of new substituted pyrazolo[3,4-b]pyridines, using water as an environmentally friendly solvent, in high to excellent yields.",

keywords = "Tetrapropylammonium bromide, One-pot, Arylglyoxals, Acetone, Solvent",

author = "Mahnaz Ezzati and Jabbar Khalafy and Marjani, {Ahmad Poursattar} and Prager, {Rolf H}",

year = "2018",

month = jun,

doi = "10.1071/CH17642",

language = "English",

volume = "71",

pages = "435--441",

journal = "Australian Journal of Chemistry",

issn = "0004-9425",

publisher = "CSIRO Publishing",

number = "6",

}

TY - JOUR

T1 - An Efficient One-Pot, Four-Component Synthesis of Pyrazolo[3,4-b]pyridines Catalyzed by Tetrapropylammonium Bromide (TPAB) in Water

AU - Ezzati, Mahnaz

AU - Khalafy, Jabbar

AU - Marjani, Ahmad Poursattar

AU - Prager, Rolf H

PY - 2018/6

Y1 - 2018/6

N2 - A novel and one-pot pseudo-four-component reaction between a series of arylglyoxals, malononitrile, 3-methyl-1-phenyl-1H-pyrazol-5-amine, and acetone in the presence of tetrapropylammonium bromide (TPAB) has been developed to synthesize a series of new substituted pyrazolo[3,4-b]pyridines, using water as an environmentally friendly solvent, in high to excellent yields.

AB - A novel and one-pot pseudo-four-component reaction between a series of arylglyoxals, malononitrile, 3-methyl-1-phenyl-1H-pyrazol-5-amine, and acetone in the presence of tetrapropylammonium bromide (TPAB) has been developed to synthesize a series of new substituted pyrazolo[3,4-b]pyridines, using water as an environmentally friendly solvent, in high to excellent yields.

KW - Tetrapropylammonium bromide

KW - One-pot

KW - Arylglyoxals

KW - Acetone

KW - Solvent

UR - http://www.scopus.com/inward/record.url?scp=85049133344&partnerID=8YFLogxK

U2 - 10.1071/CH17642

DO - 10.1071/CH17642

M3 - Article

AN - SCOPUS:85049133344

SN - 0004-9425

VL - 71

SP - 435

EP - 441

JO - Australian Journal of Chemistry

JF - Australian Journal of Chemistry

IS - 6

ER -

An Efficient One-Pot, Four-Component Synthesis of Pyrazolo[3,4-b]pyridines Catalyzed by Tetrapropylammonium Bromide (TPAB) in Water

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this