Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

Mitul Patel; Balakumar Vijayakrishnan; Julia Koeppe; Justin Chalker; Katie Doores; Benjamin Davis

doi:10.1039/c0cc03420g

Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

Mitul Patel, Balakumar Vijayakrishnan, Julia Koeppe, Justin Chalker, Katie Doores, Benjamin Davis

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Statistical correlation of mass spectrum peak broadening with product dispersity in protein conjugation reactions allows more detailed characterization of putative therapeutic conjugates.

Original language	English
Pages (from-to)	9119-9121
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	48
DOIs	https://doi.org/10.1039/c0cc03420g
Publication status	Published - 28 Dec 2010

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title = "Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry",

abstract = "Statistical correlation of mass spectrum peak broadening with product dispersity in protein conjugation reactions allows more detailed characterization of putative therapeutic conjugates.",

author = "Mitul Patel and Balakumar Vijayakrishnan and Julia Koeppe and Justin Chalker and Katie Doores and Benjamin Davis",

year = "2010",

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AU - Patel, Mitul

AU - Vijayakrishnan, Balakumar

AU - Koeppe, Julia

AU - Chalker, Justin

AU - Doores, Katie

AU - Davis, Benjamin

PY - 2010/12/28

Y1 - 2010/12/28

N2 - Statistical correlation of mass spectrum peak broadening with product dispersity in protein conjugation reactions allows more detailed characterization of putative therapeutic conjugates.

AB - Statistical correlation of mass spectrum peak broadening with product dispersity in protein conjugation reactions allows more detailed characterization of putative therapeutic conjugates.

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U2 - 10.1039/c0cc03420g

DO - 10.1039/c0cc03420g

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VL - 46

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EP - 9121

JO - Chemical Communications

JF - Chemical Communications

IS - 48

ER -

Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

Abstract

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