Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

R. D. Jolly; K. E. Dittmer; B. R. Jones; A. J. Worth; K. G. Thompson; A. C. Johnstone; D. N. Palmer; N. S. Van de Water; K. M. Hemsley; D. J. Garrick; B. G. Winchester; S. U. Walkley

doi:10.1080/00480169.2021.1928564

Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

R. D. Jolly, K. E. Dittmer, B. R. Jones, A. J. Worth, K. G. Thompson, A. C. Johnstone, D. N. Palmer, N. S. Van de Water, K. M. Hemsley, D. J. Garrick, B. G. Winchester, S. U. Walkley

Research output: Contribution to journal › Review article › peer-review

Abstract

Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.

Original language	English
Pages (from-to)	255-266
Number of pages	12
Journal	New Zealand Veterinary Journal
Volume	69
Issue number	5
Early online date	16 Jun 2021
DOIs	https://doi.org/10.1080/00480169.2021.1928564
Publication status	Published - 2021
Externally published	Yes

Keywords

animal model
animals
Genetic disorder
genetic screening
lysosomal storage disease

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Jolly, R. D., Dittmer, K. E., Jones, B. R., Worth, A. J., Thompson, K. G., Johnstone, A. C., Palmer, D. N., Van de Water, N. S., Hemsley, K. M., Garrick, D. J., Winchester, B. G., & Walkley, S. U. (2021). Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University. New Zealand Veterinary Journal, 69(5), 255-266. https://doi.org/10.1080/00480169.2021.1928564

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title = "Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University",

abstract = "Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.",

keywords = "animal model, animals, Genetic disorder, genetic screening, lysosomal storage disease",

author = "Jolly, {R. D.} and Dittmer, {K. E.} and Jones, {B. R.} and Worth, {A. J.} and Thompson, {K. G.} and Johnstone, {A. C.} and Palmer, {D. N.} and {Van de Water}, {N. S.} and Hemsley, {K. M.} and Garrick, {D. J.} and Winchester, {B. G.} and Walkley, {S. U.}",

year = "2021",

doi = "10.1080/00480169.2021.1928564",

language = "English",

volume = "69",

pages = "255--266",

journal = "New Zealand Veterinary Journal",

issn = "0048-0169",

publisher = "Taylor & Francis",

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Jolly, RD, Dittmer, KE, Jones, BR, Worth, AJ, Thompson, KG, Johnstone, AC, Palmer, DN, Van de Water, NS, Hemsley, KM, Garrick, DJ, Winchester, BG & Walkley, SU 2021, 'Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University', New Zealand Veterinary Journal, vol. 69, no. 5, pp. 255-266. https://doi.org/10.1080/00480169.2021.1928564

TY - JOUR

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T2 - a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

AU - Jolly, R. D.

AU - Dittmer, K. E.

AU - Jones, B. R.

AU - Worth, A. J.

AU - Thompson, K. G.

AU - Johnstone, A. C.

AU - Palmer, D. N.

AU - Van de Water, N. S.

AU - Hemsley, K. M.

AU - Garrick, D. J.

AU - Winchester, B. G.

AU - Walkley, S. U.

PY - 2021

Y1 - 2021

N2 - Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.

AB - Over the last 50 years, there have been major advances in knowledge and technology regarding genetic diseases, and the subsequent ability to control them in a cost-effective manner. This review traces these advances through research into genetic diseases of animals at Massey University (Palmerston North, NZ), and briefly discusses the disorders investigated during that time, with additional detail for disorders of major importance such as bovine α-mannosidosis, ovine ceroid-lipofuscinosis, canine mucopolysaccharidosis IIIA and feline hyperchylomicronaemia. The overall research has made a significant contribution to veterinary medicine, has provided new biological knowledge and advanced our understanding of similar disorders in human patients, including testing various specific therapies prior to human clinical trials.

KW - animal model

KW - animals

KW - Genetic disorder

KW - genetic screening

KW - lysosomal storage disease

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M3 - Review article

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AN - SCOPUS:85107948620

SN - 0048-0169

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JO - New Zealand Veterinary Journal

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Animal medical genetics: a historical perspective on more than 50 years of research into genetic disorders of animals at Massey University

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