Antibiotic prophylaxis prevents urinary tract infection recurrence

Research output: Contribution to journalLetterpeer-review

3 Citations (Scopus)


Question: Among children with vesicoureteral reflux, what is the efficacy of antibiotic prophylaxis, compared with placebo, in preventing urinary tract infection (UTI) recurrence?
Design:Randomized controlled trial.
Setting:19 clinical sites across the US.
Participants: Children with UTI, 2-17 months of age, who also have vesicoureteral reflux.
Intervention: Prophylaxis with trimethoprim–sulfamethoxazole vs placebo.
Outcomes: Recurrent UTI.
Original languageEnglish
Pages (from-to)778-778
Number of pages1
JournalJournal of Pediatrics
Issue number3
Publication statusPublished - 24 Feb 2015
Externally publishedYes


  • Children
  • Urinary tract infection (UTI)
  • Recurrent
  • Antimicrobial prophylaxis


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