Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients

Giovanni F.M. Strippoli; Allison Tong; David W. Johnson; Francesco Paolo Schena; Jonathan C. Craig

doi:10.1002/14651858.CD004679.pub2

Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients

Giovanni F.M. Strippoli, Allison Tong, David W. Johnson, Francesco Paolo Schena, Jonathan C. Craig

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

Abstract

People with advanced kidney disease may be treated with peritoneal dialysis where a catheter is permanently inserted into the peritoneum (lining around abdominal contents) through the abdominal wall and sterile fluid is drained in and out a few times each day. The most common serious complication is infection of the peritoneum ‐ peritonitis. This may be caused by bacteria accidentally being transferred from the catheter. This review found that nasal mupirocin reduces exit‐site/tunnel infection but not peritonitis while preoperative intravenous antibiotic prophylaxis reduces early peritonitis but not exit‐site/tunnel infection. More large scale trials are needed.

Original language	English
Article number	CD004679
Journal	Cochrane Database of Systematic Reviews
Volume	2004
Issue number	4
DOIs	https://doi.org/10.1002/14651858.CD004679.pub2
Publication status	Published - 18 Oct 2004
Externally published	Yes

Keywords

dialysis therapy
peritonitis
Antimicrobial agents

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abstract = "People with advanced kidney disease may be treated with peritoneal dialysis where a catheter is permanently inserted into the peritoneum (lining around abdominal contents) through the abdominal wall and sterile fluid is drained in and out a few times each day. The most common serious complication is infection of the peritoneum ‐ peritonitis. This may be caused by bacteria accidentally being transferred from the catheter. This review found that nasal mupirocin reduces exit‐site/tunnel infection but not peritonitis while preoperative intravenous antibiotic prophylaxis reduces early peritonitis but not exit‐site/tunnel infection. More large scale trials are needed. ",

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AU - Johnson, David W.

AU - Schena, Francesco Paolo

AU - Craig, Jonathan C.

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N2 - People with advanced kidney disease may be treated with peritoneal dialysis where a catheter is permanently inserted into the peritoneum (lining around abdominal contents) through the abdominal wall and sterile fluid is drained in and out a few times each day. The most common serious complication is infection of the peritoneum ‐ peritonitis. This may be caused by bacteria accidentally being transferred from the catheter. This review found that nasal mupirocin reduces exit‐site/tunnel infection but not peritonitis while preoperative intravenous antibiotic prophylaxis reduces early peritonitis but not exit‐site/tunnel infection. More large scale trials are needed.

AB - People with advanced kidney disease may be treated with peritoneal dialysis where a catheter is permanently inserted into the peritoneum (lining around abdominal contents) through the abdominal wall and sterile fluid is drained in and out a few times each day. The most common serious complication is infection of the peritoneum ‐ peritonitis. This may be caused by bacteria accidentally being transferred from the catheter. This review found that nasal mupirocin reduces exit‐site/tunnel infection but not peritonitis while preoperative intravenous antibiotic prophylaxis reduces early peritonitis but not exit‐site/tunnel infection. More large scale trials are needed.

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