Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients

Giovanni F.M. Strippoli, Allison Tong, David W. Johnson, Francesco Paolo Schena, Jonathan C. Craig

Research output: Contribution to journalArticlepeer-review

79 Citations (Scopus)


People with advanced kidney disease may be treated with peritoneal dialysis where a catheter is permanently inserted into the peritoneum (lining around abdominal contents) through the abdominal wall and sterile fluid is drained in and out a few times each day. The most common serious complication is infection of the peritoneum ‐ peritonitis. This may be caused by bacteria accidentally being transferred from the catheter. This review found that nasal mupirocin reduces exit‐site/tunnel infection but not peritonitis while preoperative intravenous antibiotic prophylaxis reduces early peritonitis but not exit‐site/tunnel infection. More large scale trials are needed.
Original languageEnglish
Article numberCD004679
JournalCochrane Database of Systematic Reviews
Issue number4
Publication statusPublished - 18 Oct 2004
Externally publishedYes


  • dialysis therapy
  • peritonitis
  • Antimicrobial agents


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