Antiserum to somatostatin prevents stress-induced inhibition of growth hormone secretion in the rat

Leon C. Terry, John O. Willoughby, Paul Brazeau, Joseph B. Martin, Yogesh Patel

Research output: Contribution to journalArticle

156 Citations (Scopus)

Abstract

Plasma growth hormone levels fall and remain low for several hours after stress in the rat. When antiserums to somatostatin are administered to rats prior to stress, growth hormone secretory pulses are partially restored. The results provide evidence that circulating somatostatin plays a prominent role in stress-induced inhibition of growth hormone secretion in the rat.

Original languageEnglish
Pages (from-to)565-567
Number of pages3
JournalScience
Volume192
Issue number4239
DOIs
Publication statusPublished - 7 May 1976
Externally publishedYes

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