Age-related sarcopenia contributes to functional decline, falls, fractures, morbidity and mortality of elderly people and was recognised as a disease entity (ICD-10-CM M62.84) in 2016. Whilst a consensus on the operational definition of the condition is awaited, most current definitions incorporate a combination of loss of muscle mass, strength and/or performance. Of those (10 or so) proposed to date, the vast majority of definitions use appendicular lean mass (ALM), derived from whole body dual-energy X-ray absorptiometry (DXA) scans, as the estimate of muscle mass.
- Age-related sarcopenia
- functional decline
Harvey, N. C., Kanis, J. A., Liu, E., Johansson, H., Lorentzon, M., & McCloskey, E. (2019). Appendicular lean mass and fracture risk assessment: implications for FRAX® and sarcopenia. Osteoporosis International, 30(3), 537-539. https://doi.org/10.1007/s00198-019-04904-z