Applications of visible light photoredox catalysis to the synthesis of natural products and related compounds

Thomas P. Nicholls, Daniele Leonori, Alex C. Bissember

Research output: Contribution to journalReview articlepeer-review

122 Citations (Scopus)

Abstract

Covering: 2008 to 2016 

The total synthesis of natural products and their derivatives continues to inspire organic chemists to identify and test new synthetic strategies and develop and explore novel methodology. In recent years, visible light photoredox catalysis has risen to prominence as a powerful technology that enables the selective formation of chemical bonds under mild reaction conditions. Herein we review applications of photoredox catalysis to the synthesis of natural products and related complex molecules, showcasing a range of powerful transformations that include: reductive couplings, photocycloadditions, intermolecular C-H functionalisation processes, fragmentations, and cyclisations.

Original languageEnglish
Pages (from-to)1248-1254
Number of pages7
JournalNatural Product Reports
Volume33
Issue number11
Early online date29 Jul 2016
DOIs
Publication statusPublished - 1 Nov 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016 The Royal Society of Chemistry.

Keywords

  • visible light photoredox catalysis
  • organic synthesis

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