TY - JOUR
T1 - Approaches for the detection of harmful algal blooms using oligonucleotide interactions
AU - Bruce, Karen
AU - Leterme, Sophie
AU - Ellis, Amanda
AU - Lenehan, Claire
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Blooms of microscopic algae in our waterways are becoming an increasingly important environmental concern. Many are sources of harmful biotoxins that can lead to death in humans, marine life and birds. Additionally, their biomass can cause damage to ecosystems such as oxygen depletion, displacement of species and habitat alteration. Globally, the number and frequency of harmful algal blooms has increased over the last few decades, and monitoring and detection strategies have become essential for managing these events. This review discusses developments in the use of oligonucleotide-based 'molecular probes' for the selective monitoring of algal cell numbers. Specifically, hybridisation techniques will be a focus.
AB - Blooms of microscopic algae in our waterways are becoming an increasingly important environmental concern. Many are sources of harmful biotoxins that can lead to death in humans, marine life and birds. Additionally, their biomass can cause damage to ecosystems such as oxygen depletion, displacement of species and habitat alteration. Globally, the number and frequency of harmful algal blooms has increased over the last few decades, and monitoring and detection strategies have become essential for managing these events. This review discusses developments in the use of oligonucleotide-based 'molecular probes' for the selective monitoring of algal cell numbers. Specifically, hybridisation techniques will be a focus.
KW - Bioassays
KW - Harmful algal bloom
KW - Nucleic acids
UR - http://www.scopus.com/inward/record.url?scp=84926654718&partnerID=8YFLogxK
U2 - 10.1007/s00216-014-8193-x
DO - 10.1007/s00216-014-8193-x
M3 - Review article
VL - 407
SP - 95
EP - 116
JO - Analytical and Bioanalytical Chemistry
JF - Analytical and Bioanalytical Chemistry
SN - 1618-2642
IS - 1
ER -