Arthroscopic guided synovial biopsy in rheumatology: current perspectives

Mihir Wechalekar, Malcolm Smith

    Research output: Contribution to journalReview articlepeer-review

    6 Citations (Scopus)


    Synovial membrane (SM) pathology has provided valuable insights into our current understanding of immunopathological processes and treatment responses in the inflammatory arthritides. Amongst various methods of synovial biopsy, arthroscopic techniques remain the ‘gold standard’ owing to better sampling from sites of interest, particularly in patients with partially treated disease and from areas within joints that may be difficult to access using other techniques. Newer sophisticated techniques of SM membrane analyses allow assessment of differentially regulated pathways, the knowledge of which may help elucidate diagnostic and therapeutic targets in an attempt towards developing strategies for personalised medicine in the current era of targeted biologic therapies.

    Original languageEnglish
    Pages (from-to)141-144
    Number of pages4
    JournalInternational Journal of Rheumatic Diseases
    Issue number2
    Publication statusPublished - 1 Feb 2017


    • arthroscopy
    • optimising treatment
    • synovial biopsy
    • synovial pathology


    Dive into the research topics of 'Arthroscopic guided synovial biopsy in rheumatology: current perspectives'. Together they form a unique fingerprint.

    Cite this