Assessment of the 5-minute oxygen uptake efficiency slope in children with obesity

Katrin A. Dias, Concetta E. Masterson, Matthew P. Wallen, Arnt E. Tjonna, Mansoureh S. Hosseini, Peter S.W. Davies, Peter A. Cain, Gary M. Leong, Ross Arena, Charlotte B. Ingul, Jeff S. Coombes

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Purpose: Poor cardiorespiratory fitness is associated with increased all cause morbidity and mortality. In children with obesity, maximum oxygen uptake (VO2max) may not be achieved due to reduced motivation and peripheral fatigue. We aimed to identify a valid submaximal surrogate for VO2max in children with obesity. Method: Ninety-two children with obesity (7-16 years) completed a maximal exercise treadmill test and entered a three-month exercise and/or nutrition intervention after which the exercise test was repeated (n = 63). Participants were required to reach VO2max to be included in this analysis (n = 32 at baseline and n = 13 at both time-points). The oxygen uptake efficiency slope (OUES) was determined as the slope of the line when VO2 (L/min) was plotted against logV? E. Associations between the maximal OUES, submaximal OUES (at 3, 4, 5 and 6 min of the exercise test) and VO2max were calculated. Results: In the cross-sectional analysis, V?O2max (L/min) was strongly correlated with 5-min OUES independent of Tanner puberty stage and sex (R2 = .80, p < .001). Longitudinal changes in VO2max were closely reflected by changes in 5-min OUES independent of change in percent body fat (R2 = .63, p < .05). Conclusion: The 5-min OUES is a viable alternative to VO2max when assessing children with obesity.

Original languageEnglish
Pages (from-to)350-360
Number of pages11
JournalPediatric Exercise Science
Issue number3
Publication statusPublished - Jan 2017
Externally publishedYes


  • Childhood obesity
  • Exercise intervention
  • Oxygen consumption


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