Association of Pulmonary Function with Cognitive Performance in Early, Middle and Late Adulthood

Kaarin J. Anstey, Timothy D. Windsor, Anthony F. Jorm, Helen Christensen, Bryan Rodgers

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)


Background: Pulmonary function has been associated with some measures of cognitive performance, mostly in late adulthood. This study investigated whether this association is present for a range of cognitive measures, at three stages of adulthood, and whether it remains after controlling for demographic, health and lifestyle factors. Method: The relationship between forced expiratory volume at 1 s (FEV1), a measure of pulmonary function, and cognitive test performance was examined in three cohorts aged 20-24, 40-44 and 60-64. Results: After controlling for demographic variables, smoking, physical activity, and respiratory disease, significant associations between FEV1 and cognitive test performance were evident in each age group for most cognitive measures. The association between FEV1 and measures of speed increased with age. Conclusion: FEV1 has a small but reliable positive association with cognitive test performance throughout adulthood, possibly reflecting a common physiological factor.

Original languageEnglish
Pages (from-to)230-234
Number of pages5
Issue number4
Publication statusPublished - Aug 2004
Externally publishedYes


  • Ageing
  • Biomarkers
  • Cognition
  • Physical activity
  • Pulmonary function
  • Smoking


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