Abstract
Atomic force microscopy (AFM) has now existed for over 30 years and since its beginnings the method has been applied to a variety of biological systems and has demonstrated significant advantages over other forms of microscopy such as scanning electron microscopy (SEM). For example, AFM can provide high resolution topographic images in the samples native environment, which for many biological samples may be ambient or fluid conditions The technique has developed considerably since its inception and this chapter will focus on a number of technical advances in AFM, including some novel applications readers may not be aware of, that have taken place in the last 20 years. The application of these advances to a wide variety of biological materials will also be explored.
Original language | English |
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Title of host publication | Comprehensive Nanoscience and Nanotechnology |
Editors | David L. Andrews, Robert H. Lipson, Thomas Nann |
Place of Publication | United Kingdom |
Publisher | Elsevier |
Chapter | 3.05 |
Pages | 83-104 |
Number of pages | 22 |
Volume | 3 |
Edition | 2nd |
ISBN (Electronic) | 9780128122952 |
ISBN (Print) | 9780128122969, 9780128122969 |
DOIs | |
Publication status | Published - 2019 |
Keywords
- atomic force microscopy
- biological species
- Cantilever
- imaging modes
- mass sensing
- scanning speed
- tip
- Atomic force microscopy
- Imaging modes
- Biological species
- Scanning speed
- Tip
- Mass sensing