TY - JOUR
T1 - Avian tandem repeats
T2 - Nuclear protein binding sites and the origins of short tandem repetitive DNAs
AU - Zhu, X.
AU - Testori, A.
AU - Oh, S.
AU - Skinner, J. D.
AU - Burgoyne, L. A.
PY - 1991/9/1
Y1 - 1991/9/1
N2 - A 14bp repeat isolated from the genome of a Mallard duck (Anas platyrhynchos) and a 13bp repeat isolated from the genome of a Muscovy duck (Cairina moschata) were both tandem and genus-specific. There were 2.1x106 copies of the 14bp repeat in the Mallard duck genome and 1.3x106 copies of the 13bp repeat in the Muscovy duck genome. These two repeats were not obviously homologous but each contains different transcription protein binding sites. Experimentally, the two repeats were also observed to bind nuclear proteins specifically. A sequence-selective mechanism for the expansion of short tandem repeats from single ancestral sequences containing nuclear protein binding sites is presented.
AB - A 14bp repeat isolated from the genome of a Mallard duck (Anas platyrhynchos) and a 13bp repeat isolated from the genome of a Muscovy duck (Cairina moschata) were both tandem and genus-specific. There were 2.1x106 copies of the 14bp repeat in the Mallard duck genome and 1.3x106 copies of the 13bp repeat in the Muscovy duck genome. These two repeats were not obviously homologous but each contains different transcription protein binding sites. Experimentally, the two repeats were also observed to bind nuclear proteins specifically. A sequence-selective mechanism for the expansion of short tandem repeats from single ancestral sequences containing nuclear protein binding sites is presented.
KW - Avian
KW - Evolution
KW - Nuclear protein binding site
KW - Origins and functions
KW - Short tandem repetitive DNA
UR - http://www.scopus.com/inward/record.url?scp=0026352746&partnerID=8YFLogxK
UR - https://pubmed.ncbi.nlm.nih.gov/1772445/
UR - https://www.semanticscholar.org/paper/Avian-tandem-repeats%3A-nuclear-protein-binding-sites-Zhu-Testori/298475ca302e862a15d8c378a88d574743867af4
M3 - Article
C2 - 1772445
AN - SCOPUS:0026352746
SN - 0158-5231
VL - 25
SP - 191
EP - 198
JO - Biochemistry International
JF - Biochemistry International
IS - 1
ER -