Azathioprine

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    Abstract

    Azathioprine is a synthetic purine analog. Although the drug has been used in clinical practice for approximately 50 years, the mechanism of immunosuppressive action remains poorly understood. In the late 1960s, the use of azathioprine to manage uveitis was first suggested. Subsequently, multiple case series and two randomized, placebo-controlled clinical trials have been published in support of the usefulness of this medication in patients with inflammatory eye disease.
    Original languageEnglish
    Title of host publicationIntraocular Inflammation
    EditorsManfred Zierhut, Carlos Pavesio, Shigeaki Ohno, Fernando Orefice, Narsing A. Rao
    PublisherSpringer Berlin Heidelberg
    Chapter22
    Pages309-314
    Number of pages6
    ISBN (Electronic)9783540753872
    ISBN (Print)9783540753858
    DOIs
    Publication statusPublished - 2016

    Keywords

    • pharmacokinetics
    • immunosuppressive action
    • uveitis

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