Azide-alkyne cycloadditions in a vortex fluidic device: Enhanced "on water" effects and catalysis in flow

Gabriela Oksdath-Mansilla, Renata L. Kucera, Justin M. Chalker, Colin L. Raston

Research output: Contribution to journalArticlepeer-review

Abstract

The Vortex Fluidic Device is a flow reactor that processes reactions in thin films. Running the metal-free azide-alkyne cycloaddition in this reactor revealed a dramatic enhancement of the "on water"effect. For the copper-catalyzed azide-alkyne cycloaddition, stainless steel or copper jet feeds were effective reservoirs of active copper catalyst. This journal is

Original languageEnglish
Pages (from-to)659-662
Number of pages4
JournalChemical Communications
Volume57
Issue number5
DOIs
Publication statusPublished - 16 Jan 2021

Keywords

  • Vortex fluidic device
  • azide-alkyne cycloadditions
  • Catalysis
  • flow reactor
  • Copper-Catalyzed Synthesis
  • reactive catalysts
  • Azides

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