Azide-alkyne cycloadditions in a vortex fluidic device: Enhanced "on water" effects and catalysis in flow

Gabriela Oksdath-Mansilla; Renata L. Kucera; Justin M. Chalker; Colin L. Raston

doi:10.1039/d0cc04401f

Azide-alkyne cycloadditions in a vortex fluidic device: Enhanced "on water" effects and catalysis in flow

Gabriela Oksdath-Mansilla, Renata L. Kucera, Justin M. Chalker, Colin L. Raston

College of Science and Engineering

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The Vortex Fluidic Device is a flow reactor that processes reactions in thin films. Running the metal-free azide-alkyne cycloaddition in this reactor revealed a dramatic enhancement of the "on water"effect. For the copper-catalyzed azide-alkyne cycloaddition, stainless steel or copper jet feeds were effective reservoirs of active copper catalyst. This journal is

Original language	English
Pages (from-to)	659-662
Number of pages	4
Journal	Chemical Communications
Volume	57
Issue number	5
DOIs	https://doi.org/10.1039/d0cc04401f
Publication status	Published - 16 Jan 2021

Keywords

Vortex fluidic device
azide-alkyne cycloadditions
Catalysis
flow reactor
Copper-Catalyzed Synthesis
reactive catalysts
Azides

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AU - Chalker, Justin M.

AU - Raston, Colin L.

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KW - Copper-Catalyzed Synthesis

KW - reactive catalysts

KW - Azides

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Azide-alkyne cycloadditions in a vortex fluidic device: Enhanced "on water" effects and catalysis in flow

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