TY - JOUR
T1 - Baghdadite coating formed by hybrid water-stabilized plasma spray for bioceramic applications
T2 - Mechanical and biological evaluations
AU - Pham, Duy Quang
AU - Berndt, Christopher C.
AU - Cizek, Jan
AU - Gbureck, Uwe
AU - Zreiqat, Hala
AU - Lu, Zufu
AU - Ang, Andrew Siao Ming
PY - 2021/3
Y1 - 2021/3
N2 - This work studies the mechanical and biological properties of Baghdadite (BAG, Ca3ZrSi2O9) coating manufactured on Ti6Al4V substrates by hybrid water-stabilized plasma spray (WSP-H). Hydroxyapatite (HAp, Ca10(PO4)6(OH)2) coating was produced by gas-stabilized atmospheric plasma spray and used as a reference material. Upon spraying, the BAG coating exhibited lower crystallinity than the HAp coating. Mechanical testing demonstrated superior properties of the BAG coating: its higher hardness, elastic modulus as well as a better resistance to scratch and wear. In the cell viability study, the BAG coating presented better human osteoblast attachment and proliferation on the coating surface after three days and seven days compared to the HAp counterpart. Furthermore, the gene expression study of human osteoblasts indicated that the BAG coating surface showed higher expression levels of osteogenic genes than those on the HAp coating. Overall, this study indicates that enhanced mechanical and bioactive properties can be achieved for the BAG coating compared to the benchmark HAp coating. It is therefore concluded here that the BAG coating is a potential candidate for coating orthopedic implants.
AB - This work studies the mechanical and biological properties of Baghdadite (BAG, Ca3ZrSi2O9) coating manufactured on Ti6Al4V substrates by hybrid water-stabilized plasma spray (WSP-H). Hydroxyapatite (HAp, Ca10(PO4)6(OH)2) coating was produced by gas-stabilized atmospheric plasma spray and used as a reference material. Upon spraying, the BAG coating exhibited lower crystallinity than the HAp coating. Mechanical testing demonstrated superior properties of the BAG coating: its higher hardness, elastic modulus as well as a better resistance to scratch and wear. In the cell viability study, the BAG coating presented better human osteoblast attachment and proliferation on the coating surface after three days and seven days compared to the HAp counterpart. Furthermore, the gene expression study of human osteoblasts indicated that the BAG coating surface showed higher expression levels of osteogenic genes than those on the HAp coating. Overall, this study indicates that enhanced mechanical and bioactive properties can be achieved for the BAG coating compared to the benchmark HAp coating. It is therefore concluded here that the BAG coating is a potential candidate for coating orthopedic implants.
KW - Atmospheric plasma spray
KW - Baghdadite
KW - Calcium silicate bioceramics
KW - Cell viability
KW - Gene expression
KW - Hybrid water-stabilized plasma spray
KW - Hydroxyapatite
KW - Mechanical properties
KW - Nanoindentation
UR - http://www.scopus.com/inward/record.url?scp=85099555091&partnerID=8YFLogxK
U2 - 10.1016/j.msec.2021.111873
DO - 10.1016/j.msec.2021.111873
M3 - Article
C2 - 33641891
AN - SCOPUS:85099555091
SN - 0928-4931
VL - 122
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
M1 - 111873
ER -