Baghdadite coating formed by hybrid water-stabilized plasma spray for bioceramic applications: Mechanical and biological evaluations

Duy Quang Pham, Christopher C. Berndt, Jan Cizek, Uwe Gbureck, Hala Zreiqat, Zufu Lu, Andrew Siao Ming Ang

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

This work studies the mechanical and biological properties of Baghdadite (BAG, Ca3ZrSi2O9) coating manufactured on Ti6Al4V substrates by hybrid water-stabilized plasma spray (WSP-H). Hydroxyapatite (HAp, Ca10(PO4)6(OH)2) coating was produced by gas-stabilized atmospheric plasma spray and used as a reference material. Upon spraying, the BAG coating exhibited lower crystallinity than the HAp coating. Mechanical testing demonstrated superior properties of the BAG coating: its higher hardness, elastic modulus as well as a better resistance to scratch and wear. In the cell viability study, the BAG coating presented better human osteoblast attachment and proliferation on the coating surface after three days and seven days compared to the HAp counterpart. Furthermore, the gene expression study of human osteoblasts indicated that the BAG coating surface showed higher expression levels of osteogenic genes than those on the HAp coating. Overall, this study indicates that enhanced mechanical and bioactive properties can be achieved for the BAG coating compared to the benchmark HAp coating. It is therefore concluded here that the BAG coating is a potential candidate for coating orthopedic implants.

Original languageEnglish
Article number111873
Number of pages16
JournalMaterials Science and Engineering C
Volume122
DOIs
Publication statusPublished - Mar 2021
Externally publishedYes

Keywords

  • Atmospheric plasma spray
  • Baghdadite
  • Calcium silicate bioceramics
  • Cell viability
  • Gene expression
  • Hybrid water-stabilized plasma spray
  • Hydroxyapatite
  • Mechanical properties
  • Nanoindentation

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