Baroreflex sensitivity derived from the Valsalva manoeuvre: A physiological protective factor for anxiety induced by breathing CO2-enriched air

Chiara Di Credico; Michael Rosenberg; Peter Eastwood; Peter Buzzacott; Jennifer Walsh

doi:10.1016/j.ijpsycho.2022.06.019

Baroreflex sensitivity derived from the Valsalva manoeuvre: A physiological protective factor for anxiety induced by breathing CO₂-enriched air

Chiara Di Credico, Michael Rosenberg, Peter Eastwood, Peter Buzzacott, Jennifer Walsh

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

This study aimed to determine the capacity of baroreflex sensitivity, derived from the Valsalva manoeuvre (BRS_v), to predict state anxiety induced by a biological stressor (CO₂ inhalation). Healthy adults (n = 50) breathed 7.5 % CO₂-enriched air for 8 min, preceded and followed by breathing medical air for 5 min. State anxiety was evaluated with a visual analogue scale. Anxiety sensitivity (Anxiety Sensitivity Index-3; ASI-3) and trait anxiety (Trait form of the State-Trait Anxiety Inventory; STAI_T) served as cognitive-affective predictors. BRS_v was adopted as a physiological predictor. Multiple regression analysis revealed that BRS_v predicted lower anxiety during CO₂ exposure, and attenuated the effect of ASI-3 in increasing anxiety. No significant effects were found for STAI_T. This is the first study to identify baroreflex sensitivity as a strong protective physiological factor for anxiety beyond the effect of anxiety sensitivity.

Original language	English
Pages (from-to)	101-109
Number of pages	9
Journal	International Journal of Psychophysiology
Volume	179
DOIs	https://doi.org/10.1016/j.ijpsycho.2022.06.019
Publication status	Published - Sept 2022
Externally published	Yes

Keywords

Anxiety sensitivity
Baroreceptor reflex
Cardiac vagal activity
CO challenge test
Emotions
Hypercapnia

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title = "Baroreflex sensitivity derived from the Valsalva manoeuvre: A physiological protective factor for anxiety induced by breathing CO2-enriched air",

abstract = "This study aimed to determine the capacity of baroreflex sensitivity, derived from the Valsalva manoeuvre (BRS_v), to predict state anxiety induced by a biological stressor (CO2 inhalation). Healthy adults (n = 50) breathed 7.5 % CO2-enriched air for 8 min, preceded and followed by breathing medical air for 5 min. State anxiety was evaluated with a visual analogue scale. Anxiety sensitivity (Anxiety Sensitivity Index-3; ASI-3) and trait anxiety (Trait form of the State-Trait Anxiety Inventory; STAI_T) served as cognitive-affective predictors. BRS_v was adopted as a physiological predictor. Multiple regression analysis revealed that BRS_v predicted lower anxiety during CO2 exposure, and attenuated the effect of ASI-3 in increasing anxiety. No significant effects were found for STAI_T. This is the first study to identify baroreflex sensitivity as a strong protective physiological factor for anxiety beyond the effect of anxiety sensitivity.",

keywords = "Anxiety sensitivity, Baroreceptor reflex, Cardiac vagal activity, CO challenge test, Emotions, Hypercapnia",

author = "{Di Credico}, Chiara and Michael Rosenberg and Peter Eastwood and Peter Buzzacott and Jennifer Walsh",

year = "2022",

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doi = "10.1016/j.ijpsycho.2022.06.019",

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AU - Rosenberg, Michael

AU - Eastwood, Peter

AU - Buzzacott, Peter

AU - Walsh, Jennifer

PY - 2022/9

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ER -

Baroreflex sensitivity derived from the Valsalva manoeuvre: A physiological protective factor for anxiety induced by breathing CO₂-enriched air

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Keywords

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