Base organocatalyst mediated annulation of arylglyoxalmonohydrates with 2,4-dihydroxyquinoline to form new pyranodiquinolinones

Mehdi Rimaz, Zahra Jalalian, Hossein Mousavi, Rolf Prager

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

A mild and efficient method for the chemoselective synthesis of 7-aryloyl-5. H-pyrano[3,2-c:5,6-c']diquinoline-6,8(7. H,9. H)-diones, representing a new class of substituted pyranodiquinolinone derivatives, via the annulation of arylglyoxalmonohydrates with 2,4-dihydroxyquinoline in the presence of catalytic DBU is described. The salient features of this procedure are high chemo- and regioselectivity, short reaction times, good to high yields, easy work-up, and operational simplicity.

Original languageEnglish
Pages (from-to)105-109
Number of pages5
JournalTetrahedron Letters
Volume57
Issue number1
Early online date2016
DOIs
Publication statusPublished - 6 Jan 2016

Keywords

  • Arylglyoxalmonohydrate
  • One-pot
  • Organocatalyst
  • Pyranoquinoline

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