Baseline characteristics of participants in the NAVKIDS2 trial: a patient navigator program in children with chronic kidney disease

Chandana Guha; Rabia Khalid; Anita van Zwieten; Anna Francis; Carmel M. Hawley; Allison Jauré; Armando Teixeira-Pinto; Alistair R. Mallard; Amelie Bernier-Jean; David W. Johnson; Deirdre Hahn; Donna Reidlinger; Elaine M. Pascoe; Elizabeth G. Ryan; Fiona Mackie; Hugh J. McCarthy; Jonathan C. Craig; Julie Varghese; Charani Kiriwandeniya; Kirsten Howard; Nicholas G. Larkins; Luke Macauley; Amanda Walker; Martin Howell; Michelle Irving; Patrina H.Y. Caldwell; Reginald Woodleigh; Shilpanjali Jesudason; Simon A. Carter; Sean E. Kennedy; Stephen I. Alexander; Steven McTaggart; Germaine Wong

doi:10.1007/s00467-022-05772-2

Baseline characteristics of participants in the NAVKIDS² trial: a patient navigator program in children with chronic kidney disease

Chandana Guha
, Rabia Khalid
, Anita van Zwieten
, Anna Francis
, Carmel M. Hawley
, Allison Jauré
, Armando Teixeira-Pinto
, Alistair R. Mallard
, Amelie Bernier-Jean
, David W. Johnson
, Deirdre Hahn
, Donna Reidlinger
, Elaine M. Pascoe
, Elizabeth G. Ryan
, Fiona Mackie
, Hugh J. McCarthy
, Jonathan C. Craig
, Julie Varghese
, Charani Kiriwandeniya
, Kirsten Howard

Nicholas G. Larkins, Luke Macauley, Amanda Walker, Martin Howell, Michelle Irving, Patrina H.Y. Caldwell, Reginald Woodleigh, Shilpanjali Jesudason, Simon A. Carter, Sean E. Kennedy, Stephen I. Alexander, Steven McTaggart, Germaine Wong

College of Medicine and Public Health

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Background: Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to overcome barriers to accessing health services through care coordination. This trial aims to determine the effectiveness of a patient navigator program in children with CKD.

Methods: The NAVKIDS² trial is a multi-center, waitlisted, randomized controlled trial of patient navigators in children with CKD conducted at five sites across Australia. Children (0–16 years) with CKD from low socioeconomic status rural or remote areas were randomized to an intervention group or a waitlisted control group (to receive intervention after 6 months). The study primary and secondary endpoints include the self-rated health (SRH) (primary), and utility-based quality of life, progression of kidney dysfunction of the child, SRH, and satisfaction with healthcare of the caregiver at 6 months post-randomization.

Results: The trial completed recruitment in October 2021 with expected completion of follow-up by October 2022. There were 162 patients enrolled with 80 and 82 patients randomized to the immediate intervention and waitlisted groups, respectively. Fifty-eight (36%) participants were from regional/remote areas, with a median (IQR) age of 9.5 (5.0, 13.0) years, 46% were of European Australian ethnicity, and 65% were male. A total of 109 children (67%) had CKD stages 1–5, 42 (26%) were transplant recipients, and 11 (7%) were receiving dialysis.

Conclusion: The NAVKIDS² trial is designed to evaluate the effectiveness of patient navigation in children with CKD from families experiencing socioeconomic disadvantage. Graphical abstract: [Figure not available: see fulltext.].

Original language	English
Pages (from-to)	1577-1590
Number of pages	14
Journal	PEDIATRIC NEPHROLOGY
Volume	38
Issue number	5
Early online date	20 Oct 2022
DOIs	https://doi.org/10.1007/s00467-022-05772-2
Publication status	Published - May 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adolescents
Children
Chronic kidney disease
Patient navigator
Social determinants of health
Socioeconomic status

Access to Document

10.1007/s00467-022-05772-2Licence: In Copyright

https://rdcu.be/c1ZclLicence: In Copyright

Cite this

Guha, C., Khalid, R., van Zwieten, A., Francis, A., Hawley, C. M., Jauré, A., Teixeira-Pinto, A., Mallard, A. R., Bernier-Jean, A., Johnson, D. W., Hahn, D., Reidlinger, D., Pascoe, E. M., Ryan, E. G., Mackie, F., McCarthy, H. J., Craig, J. C., Varghese, J., Kiriwandeniya, C., ... Wong, G. (2023). Baseline characteristics of participants in the NAVKIDS² trial: a patient navigator program in children with chronic kidney disease. PEDIATRIC NEPHROLOGY, 38(5), 1577-1590. https://doi.org/10.1007/s00467-022-05772-2

@article{94eb8d224687406eb920223ce695b386,

title = "Baseline characteristics of participants in the NAVKIDS2 trial: a patient navigator program in children with chronic kidney disease",

abstract = "Background: Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to overcome barriers to accessing health services through care coordination. This trial aims to determine the effectiveness of a patient navigator program in children with CKD. Methods: The NAVKIDS2 trial is a multi-center, waitlisted, randomized controlled trial of patient navigators in children with CKD conducted at five sites across Australia. Children (0–16 years) with CKD from low socioeconomic status rural or remote areas were randomized to an intervention group or a waitlisted control group (to receive intervention after 6 months). The study primary and secondary endpoints include the self-rated health (SRH) (primary), and utility-based quality of life, progression of kidney dysfunction of the child, SRH, and satisfaction with healthcare of the caregiver at 6 months post-randomization. Results: The trial completed recruitment in October 2021 with expected completion of follow-up by October 2022. There were 162 patients enrolled with 80 and 82 patients randomized to the immediate intervention and waitlisted groups, respectively. Fifty-eight (36\%) participants were from regional/remote areas, with a median (IQR) age of 9.5 (5.0, 13.0) years, 46\% were of European Australian ethnicity, and 65\% were male. A total of 109 children (67\%) had CKD stages 1–5, 42 (26\%) were transplant recipients, and 11 (7\%) were receiving dialysis. Conclusion: The NAVKIDS2 trial is designed to evaluate the effectiveness of patient navigation in children with CKD from families experiencing socioeconomic disadvantage. Graphical abstract: [Figure not available: see fulltext.].",

keywords = "Adolescents, Children, Chronic kidney disease, Patient navigator, Social determinants of health, Socioeconomic status",

author = "Chandana Guha and Rabia Khalid and \{van Zwieten\}, Anita and Anna Francis and Hawley, \{Carmel M.\} and Allison Jaur{\'e} and Armando Teixeira-Pinto and Mallard, \{Alistair R.\} and Amelie Bernier-Jean and Johnson, \{David W.\} and Deirdre Hahn and Donna Reidlinger and Pascoe, \{Elaine M.\} and Ryan, \{Elizabeth G.\} and Fiona Mackie and McCarthy, \{Hugh J.\} and Craig, \{Jonathan C.\} and Julie Varghese and Charani Kiriwandeniya and Kirsten Howard and Larkins, \{Nicholas G.\} and Luke Macauley and Amanda Walker and Martin Howell and Michelle Irving and Caldwell, \{Patrina H.Y.\} and Reginald Woodleigh and Shilpanjali Jesudason and Carter, \{Simon A.\} and Kennedy, \{Sean E.\} and Alexander, \{Stephen I.\} and Steven McTaggart and Germaine Wong",

year = "2023",

month = may,

doi = "10.1007/s00467-022-05772-2",

language = "English",

volume = "38",

pages = "1577--1590",

journal = "PEDIATRIC NEPHROLOGY",

issn = "0931-041X",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "5",

}

Guha, C, Khalid, R, van Zwieten, A, Francis, A, Hawley, CM, Jauré, A, Teixeira-Pinto, A, Mallard, AR, Bernier-Jean, A, Johnson, DW, Hahn, D, Reidlinger, D, Pascoe, EM, Ryan, EG, Mackie, F, McCarthy, HJ, Craig, JC, Varghese, J, Kiriwandeniya, C, Howard, K, Larkins, NG, Macauley, L, Walker, A, Howell, M, Irving, M, Caldwell, PHY, Woodleigh, R, Jesudason, S, Carter, SA, Kennedy, SE, Alexander, SI, McTaggart, S & Wong, G 2023, 'Baseline characteristics of participants in the NAVKIDS² trial: a patient navigator program in children with chronic kidney disease', PEDIATRIC NEPHROLOGY, vol. 38, no. 5, pp. 1577-1590. https://doi.org/10.1007/s00467-022-05772-2

TY - JOUR

T1 - Baseline characteristics of participants in the NAVKIDS2 trial

T2 - a patient navigator program in children with chronic kidney disease

AU - Guha, Chandana

AU - Khalid, Rabia

AU - van Zwieten, Anita

AU - Francis, Anna

AU - Hawley, Carmel M.

AU - Jauré, Allison

AU - Teixeira-Pinto, Armando

AU - Mallard, Alistair R.

AU - Bernier-Jean, Amelie

AU - Johnson, David W.

AU - Hahn, Deirdre

AU - Reidlinger, Donna

AU - Pascoe, Elaine M.

AU - Ryan, Elizabeth G.

AU - Mackie, Fiona

AU - McCarthy, Hugh J.

AU - Craig, Jonathan C.

AU - Varghese, Julie

AU - Kiriwandeniya, Charani

AU - Howard, Kirsten

AU - Larkins, Nicholas G.

AU - Macauley, Luke

AU - Walker, Amanda

AU - Howell, Martin

AU - Irving, Michelle

AU - Caldwell, Patrina H.Y.

AU - Woodleigh, Reginald

AU - Jesudason, Shilpanjali

AU - Carter, Simon A.

AU - Kennedy, Sean E.

AU - Alexander, Stephen I.

AU - McTaggart, Steven

AU - Wong, Germaine

PY - 2023/5

Y1 - 2023/5

N2 - Background: Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to overcome barriers to accessing health services through care coordination. This trial aims to determine the effectiveness of a patient navigator program in children with CKD. Methods: The NAVKIDS2 trial is a multi-center, waitlisted, randomized controlled trial of patient navigators in children with CKD conducted at five sites across Australia. Children (0–16 years) with CKD from low socioeconomic status rural or remote areas were randomized to an intervention group or a waitlisted control group (to receive intervention after 6 months). The study primary and secondary endpoints include the self-rated health (SRH) (primary), and utility-based quality of life, progression of kidney dysfunction of the child, SRH, and satisfaction with healthcare of the caregiver at 6 months post-randomization. Results: The trial completed recruitment in October 2021 with expected completion of follow-up by October 2022. There were 162 patients enrolled with 80 and 82 patients randomized to the immediate intervention and waitlisted groups, respectively. Fifty-eight (36%) participants were from regional/remote areas, with a median (IQR) age of 9.5 (5.0, 13.0) years, 46% were of European Australian ethnicity, and 65% were male. A total of 109 children (67%) had CKD stages 1–5, 42 (26%) were transplant recipients, and 11 (7%) were receiving dialysis. Conclusion: The NAVKIDS2 trial is designed to evaluate the effectiveness of patient navigation in children with CKD from families experiencing socioeconomic disadvantage. Graphical abstract: [Figure not available: see fulltext.].

AB - Background: Children with chronic kidney disease (CKD) require multidisciplinary care to meet their complex healthcare needs. Patient navigators are trained non-medical personnel who assist patients and caregivers to overcome barriers to accessing health services through care coordination. This trial aims to determine the effectiveness of a patient navigator program in children with CKD. Methods: The NAVKIDS2 trial is a multi-center, waitlisted, randomized controlled trial of patient navigators in children with CKD conducted at five sites across Australia. Children (0–16 years) with CKD from low socioeconomic status rural or remote areas were randomized to an intervention group or a waitlisted control group (to receive intervention after 6 months). The study primary and secondary endpoints include the self-rated health (SRH) (primary), and utility-based quality of life, progression of kidney dysfunction of the child, SRH, and satisfaction with healthcare of the caregiver at 6 months post-randomization. Results: The trial completed recruitment in October 2021 with expected completion of follow-up by October 2022. There were 162 patients enrolled with 80 and 82 patients randomized to the immediate intervention and waitlisted groups, respectively. Fifty-eight (36%) participants were from regional/remote areas, with a median (IQR) age of 9.5 (5.0, 13.0) years, 46% were of European Australian ethnicity, and 65% were male. A total of 109 children (67%) had CKD stages 1–5, 42 (26%) were transplant recipients, and 11 (7%) were receiving dialysis. Conclusion: The NAVKIDS2 trial is designed to evaluate the effectiveness of patient navigation in children with CKD from families experiencing socioeconomic disadvantage. Graphical abstract: [Figure not available: see fulltext.].

KW - Adolescents

KW - Children

KW - Chronic kidney disease

KW - Patient navigator

KW - Social determinants of health

KW - Socioeconomic status

UR - https://www.scopus.com/pages/publications/85140322657

UR - http://purl.org/au-research/grants/NHMRC/1170021

U2 - 10.1007/s00467-022-05772-2

DO - 10.1007/s00467-022-05772-2

M3 - Article

C2 - 36264432

AN - SCOPUS:85140322657

SN - 0931-041X

VL - 38

SP - 1577

EP - 1590

JO - PEDIATRIC NEPHROLOGY

JF - PEDIATRIC NEPHROLOGY

IS - 5

ER -