Biomedical applications of polyelectrolyte coated spherical gold nanoparticles

Melanie A. Fuller, Ingo Köper

Research output: Contribution to journalReview articlepeer-review

43 Citations (Scopus)
18 Downloads (Pure)


Surface modified gold nanoparticles are becoming more and more popular for use in biomaterials due to the possibility for specific targeting and increased biocompatibility. This review provides a summary of the recent literature surrounding polyelectrolyte coatings on spherical gold nanoparticles and their potential biomedical applications. The synthesis and layer-by layer coating approach are briefly discussed together with common characterisation methods. The potential applications and recent developments in drug delivery, gene therapy, photothermal therapy and imaging are summarized as well as the effects on cellular uptake and toxicity. Finally, the future outlook for polyelectrolyte coated gold nanoparticles is explored, focusing on their use in biomedicine. [Figure not available: see fulltext.].

Original languageEnglish
Article number11
JournalNano Convergence
Issue number1
Publication statusPublished - 24 Apr 2019
Externally publishedYes

Bibliographical note

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.


  • Biomedical
  • Gold
  • Gold nanoparticles
  • Nanoparticles
  • Polyelectrolyte


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