Abstract
Different kinds of harmful raw materials are used in brick kilns for baking bricks, thus exerting negative effects on the health of brick kiln workers and nearby residents. The comet assay technique monitors DNA damage in lymphocytes of brick kiln workers. Blood samples were collected from 150 participants to conduct comet assay. The results indicated a highly significant increase (p <.0001) in DNA damage in brick kiln workers (171.9 ± 62.1) as compared with the control group (101.9 ± 48.3). Duration of occupational exposure had positive correlation (r =.823, p <.05) with DNA damage. Age and tobacco use had significant effects on total comet score (TCS) of exposed group as compared to control group (p <.05). In summary, these findings indicate greater genotoxicity in brick kiln workers.
| Original language | English |
|---|---|
| Pages (from-to) | 115-120 |
| Number of pages | 6 |
| Journal | Archives of Environmental and Occupational Health |
| Volume | 73 |
| Issue number | 2 |
| Early online date | 5 Apr 2017 |
| DOIs | |
| Publication status | Published - Mar 2018 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Biomonitoring
- brick kilns
- brick kiln workers
- comet assay
- DNA damage
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