Blood pressure and cerebral ischemia: A continuing dilemma

Rebecca F. Gottesman, John Chalmers

Research output: Contribution to journalEditorial


Classical neurologic teaching suggests that a higher cerebral systemic blood pressure (BP) be targeted for individuals with occlusive carotid disease, in order to improve cerebral perfusion through collaterals. This conflicts, however, with observational population-based studies and clinical trials supporting better outcomes associated with lower BPs. In this issue of Neurology®, Powers et al.1 evaluate nonsurgical controls from the Carotid Occlusion Surgery Study (COSS) and report lower rates of stroke recurrence in individuals maintained at a follow-up BP of 130/85 mm Hg or lower
Original languageEnglish
Pages (from-to)1018-1019
Number of pages3
Issue number12
Publication statusPublished - 25 Mar 2014
Externally publishedYes


  • blood pressure
  • occlusive carotid disease


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