Body mass index and breast size in women: Same or different genes

Tracey Wade, Gu Zhu, Nicholas Martin

    Research output: Contribution to journalArticlepeer-review

    22 Citations (Scopus)

    Abstract

    The objective of the current study was to investigate the heritability of breast size and the degree to which this heritability is shared with BMI. In a sample of 1010 females twins (mean age 35 years; SD = 2.1; range 28-40), self-report data pertaining to bra cup size and body mass index (BMI) was collected in the context of self-report data and an interview relating to disordered eating respectively. In a sample of 348 complete twin pairs who completed data collection (226 MZ pairs and 122 DZ pairs and 360 incomplete pairs (170 MZ and 190 DZ)), we found that the heritability of bra cup size was 56%. Of this genetic variance, one third is in common with genes influencing body mass index, and two thirds (41% of total variance) is unique to breast size, with some directional evidence of non-additive genetic variation. The implications of these findings with respect to previous research linking breast size with reproductive potential are discussed.

    Original languageEnglish
    Pages (from-to)450-454
    Number of pages5
    JournalTwin Research & Human Genetics
    Volume13
    Issue number5
    DOIs
    Publication statusPublished - Oct 2010

    Keywords

    • Bivariate Cholesky
    • Body mass index
    • Breast size
    • Heritability

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