Body Temperature Measurements for Metabolic Phenotyping in Mice

Carola Meyer, Youichirou Ootsuka, Andrej Romanovsky

    Research output: Contribution to journalArticlepeer-review

    76 Citations (Scopus)
    96 Downloads (Pure)

    Abstract

    Endothermic organisms rely on tightly balanced energy budgets to maintain a regulated body temperature and body mass. Metabolic phenotyping of mice, therefore, often includes the recording of body temperature. Thermometry in mice is conducted at various sites, using various devices and measurement practices, ranging from single-time probing to continuous temperature imaging. Whilst there is broad agreement that body temperature data is of value, procedural considerations of body temperature measurements in the context of metabolic phenotyping are missing. Here, we provide an overview of the various methods currently available for gathering body temperature data from mice. We explore the scope and limitations of thermometry in mice, with the hope of assisting researchers in the selection of appropriate approaches, and conditions, for comprehensive mouse phenotypic analyses.

    Original languageEnglish
    Article number520
    Number of pages13
    JournalFrontiers in Physiology
    Volume8
    DOIs
    Publication statusPublished - 31 Jul 2017

    Keywords

    • body temperature
    • metabolism
    • mouse
    • mouse models
    • phenotyping
    • telemetric recordings
    • thermography

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