Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7

Michael Gütschow; Jean Jacques Vanden Eynde; Josef Jampilek; Cong Bao Kang; Arduino A. Mangoni; Paola Fossa; Rafik Karaman; Andrea Trabocchi; Peter J.H. Scott; Jóhannes Reynisson; Simona Rapposelli; Stefania Galdiero; Jean Yves Winum; Chiara Brullo; Katalin Prokai-Tatrai; Arun K. Sharma; Matthieu Schapira; Yasu Taka Azuma; Laura Cerchia; Mariana Spetea; Giangiacomo Torri; Simona Collina; Athina Geronikaki; Alfonso T. García-Sosa; M. Helena Vasconcelos; Maria Emília Sousa; Ivan Kosalec; Tiziano Tuccinardi; Iola F. Duarte; Jorge A.R. Salvador; Massimo Bertinaria; Maurizio Pellecchia; Jussara Amato; Giulio Rastelli; Paula A.C. Gomes; Rita C. Guedes; Jean Marc Sabatier; Ana Estévez-Braun; Bruno Pagano; Stefano Mangani; Rino Ragno; George Kokotos; Margherita Brindisi; Florenci V. González; Fernanda Borges; Mariarosaria Miloso; Jarkko Rautio; Diego Muñoz-Torrero

doi:10.3390/molecules25132968

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7

Michael Gütschow, Jean Jacques Vanden Eynde, Josef Jampilek, Cong Bao Kang, Arduino A. Mangoni, Paola Fossa, Rafik Karaman, Andrea Trabocchi, Peter J.H. Scott, Jóhannes Reynisson, Simona Rapposelli, Stefania Galdiero, Jean Yves Winum, Chiara Brullo, Katalin Prokai-Tatrai, Arun K. Sharma, Matthieu Schapira, Yasu Taka Azuma, Laura Cerchia, Mariana SpeteaGiangiacomo Torri, Simona Collina, Athina Geronikaki, Alfonso T. García-Sosa, M. Helena Vasconcelos, Maria Emília Sousa, Ivan Kosalec, Tiziano Tuccinardi, Iola F. Duarte, Jorge A.R. Salvador, Massimo Bertinaria, Maurizio Pellecchia, Jussara Amato, Giulio Rastelli, Paula A.C. Gomes, Rita C. Guedes, Jean Marc Sabatier, Ana Estévez-Braun, Bruno Pagano, Stefano Mangani, Rino Ragno, George Kokotos, Margherita Brindisi, Florenci V. González, Fernanda Borges, Mariarosaria Miloso, Jarkko Rautio, Diego Muñoz-Torrero

College of Medicine and Public Health

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Abstract

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules. In these editorials, we highlight in brief reports (of about one hundred words) a number of recently published articles that describe crucial findings, such as the discovery of novel drug targets and mechanisms of action or novel classes of drugs, which may inspire future medicinal chemistry endeavors devoted to addressing prime unmet medical needs.

Original language	English
Article number	2968
Number of pages	22
Journal	Molecules
Volume	25
Issue number	13
Early online date	28 Jun 2020
DOIs	https://doi.org/10.3390/molecules25132968
Publication status	Published - 1 Jul 2020

Bibliographical note

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

Keywords

medicinal chemistry
drug targets
classes of drugs

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10.3390/molecules25132968Licence: CC BY

Published versionFinal published version, 2.84 MBLicence: CC BY

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Gütschow, M., Eynde, J. J. V., Jampilek, J., Kang, C. B., Mangoni, A. A., Fossa, P., Karaman, R., Trabocchi, A., Scott, P. J. H., Reynisson, J., Rapposelli, S., Galdiero, S., Winum, J. Y., Brullo, C., Prokai-Tatrai, K., Sharma, A. K., Schapira, M., Azuma, Y. T., Cerchia, L., ... Muñoz-Torrero, D. (2020). Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7. Molecules, 25(13), Article 2968. https://doi.org/10.3390/molecules25132968

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abstract = "Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules. In these editorials, we highlight in brief reports (of about one hundred words) a number of recently published articles that describe crucial findings, such as the discovery of novel drug targets and mechanisms of action or novel classes of drugs, which may inspire future medicinal chemistry endeavors devoted to addressing prime unmet medical needs.",

keywords = "medicinal chemistry, drug targets, classes of drugs",

author = "Michael G{\"u}tschow and Eynde, {Jean Jacques Vanden} and Josef Jampilek and Kang, {Cong Bao} and Mangoni, {Arduino A.} and Paola Fossa and Rafik Karaman and Andrea Trabocchi and Scott, {Peter J.H.} and J{\'o}hannes Reynisson and Simona Rapposelli and Stefania Galdiero and Winum, {Jean Yves} and Chiara Brullo and Katalin Prokai-Tatrai and Sharma, {Arun K.} and Matthieu Schapira and Azuma, {Yasu Taka} and Laura Cerchia and Mariana Spetea and Giangiacomo Torri and Simona Collina and Athina Geronikaki and Garc{\'i}a-Sosa, {Alfonso T.} and Vasconcelos, {M. Helena} and Sousa, {Maria Em{\'i}lia} and Ivan Kosalec and Tiziano Tuccinardi and Duarte, {Iola F.} and Salvador, {Jorge A.R.} and Massimo Bertinaria and Maurizio Pellecchia and Jussara Amato and Giulio Rastelli and Gomes, {Paula A.C.} and Guedes, {Rita C.} and Sabatier, {Jean Marc} and Ana Est{\'e}vez-Braun and Bruno Pagano and Stefano Mangani and Rino Ragno and George Kokotos and Margherita Brindisi and Gonz{\'a}lez, {Florenci V.} and Fernanda Borges and Mariarosaria Miloso and Jarkko Rautio and Diego Mu{\~n}oz-Torrero",

note = "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).",

year = "2020",

month = jul,

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doi = "10.3390/molecules25132968",

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Gütschow, M, Eynde, JJV, Jampilek, J, Kang, CB, Mangoni, AA, Fossa, P, Karaman, R, Trabocchi, A, Scott, PJH, Reynisson, J, Rapposelli, S, Galdiero, S, Winum, JY, Brullo, C, Prokai-Tatrai, K, Sharma, AK, Schapira, M, Azuma, YT, Cerchia, L, Spetea, M, Torri, G, Collina, S, Geronikaki, A, García-Sosa, AT, Vasconcelos, MH, Sousa, ME, Kosalec, I, Tuccinardi, T, Duarte, IF, Salvador, JAR, Bertinaria, M, Pellecchia, M, Amato, J, Rastelli, G, Gomes, PAC, Guedes, RC, Sabatier, JM, Estévez-Braun, A, Pagano, B, Mangani, S, Ragno, R, Kokotos, G, Brindisi, M, González, FV, Borges, F, Miloso, M, Rautio, J & Muñoz-Torrero, D 2020, 'Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7', Molecules, vol. 25, no. 13, 2968. https://doi.org/10.3390/molecules25132968

TY - JOUR

T1 - Breakthroughs in Medicinal Chemistry

T2 - New Targets and Mechanisms, New Drugs, New Hopes-7

AU - Gütschow, Michael

AU - Eynde, Jean Jacques Vanden

AU - Jampilek, Josef

AU - Kang, Cong Bao

AU - Mangoni, Arduino A.

AU - Fossa, Paola

AU - Karaman, Rafik

AU - Trabocchi, Andrea

AU - Scott, Peter J.H.

AU - Reynisson, Jóhannes

AU - Rapposelli, Simona

AU - Galdiero, Stefania

AU - Winum, Jean Yves

AU - Brullo, Chiara

AU - Prokai-Tatrai, Katalin

AU - Sharma, Arun K.

AU - Schapira, Matthieu

AU - Azuma, Yasu Taka

AU - Cerchia, Laura

AU - Spetea, Mariana

AU - Torri, Giangiacomo

AU - Collina, Simona

AU - Geronikaki, Athina

AU - García-Sosa, Alfonso T.

AU - Vasconcelos, M. Helena

AU - Sousa, Maria Emília

AU - Kosalec, Ivan

AU - Tuccinardi, Tiziano

AU - Duarte, Iola F.

AU - Salvador, Jorge A.R.

AU - Bertinaria, Massimo

AU - Pellecchia, Maurizio

AU - Amato, Jussara

AU - Rastelli, Giulio

AU - Gomes, Paula A.C.

AU - Guedes, Rita C.

AU - Sabatier, Jean Marc

AU - Estévez-Braun, Ana

AU - Pagano, Bruno

AU - Mangani, Stefano

AU - Ragno, Rino

AU - Kokotos, George

AU - Brindisi, Margherita

AU - González, Florenci V.

AU - Borges, Fernanda

AU - Miloso, Mariarosaria

AU - Rautio, Jarkko

AU - Muñoz-Torrero, Diego

N1 - This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PY - 2020/7/1

Y1 - 2020/7/1

N2 - Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules. In these editorials, we highlight in brief reports (of about one hundred words) a number of recently published articles that describe crucial findings, such as the discovery of novel drug targets and mechanisms of action or novel classes of drugs, which may inspire future medicinal chemistry endeavors devoted to addressing prime unmet medical needs.

AB - Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules. In these editorials, we highlight in brief reports (of about one hundred words) a number of recently published articles that describe crucial findings, such as the discovery of novel drug targets and mechanisms of action or novel classes of drugs, which may inspire future medicinal chemistry endeavors devoted to addressing prime unmet medical needs.

KW - medicinal chemistry

KW - drug targets

KW - classes of drugs

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U2 - 10.3390/molecules25132968

DO - 10.3390/molecules25132968

M3 - Editorial

C2 - 32605268

AN - SCOPUS:85087420605

SN - 1420-3049

VL - 25

JO - Molecules

JF - Molecules

IS - 13

M1 - 2968

ER -

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7

Abstract

Bibliographical note

Keywords

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