Butyllithium-mediated coupling of aryl bromides with ketones under in-situ-quench (ISQ) conditions: an efficient one-step protocol applicable to microreactor technology

Sachio Goto; Janna Velder; Sherif El Sheikh; Yuki Sakamoto; Masatoshi Mitani; Sait Elmas; Andreas Adler; Anne Becker; Jörg-Martin Neudörfl; Johann Lex; Hans-Günther Schmalz

Butyllithium-mediated coupling of aryl bromides with ketones under in-situ-quench (ISQ) conditions: an efficient one-step protocol applicable to microreactor technology

Sachio Goto, Janna Velder, Sherif El Sheikh, Yuki Sakamoto, Masatoshi Mitani, Sait Elmas, Andreas Adler, Anne Becker, Jörg-Martin Neudörfl, Johann Lex, Hans-Günther Schmalz

Flinders Institute for Nanoscale Science and Technology

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Original language	English
Pages (from-to)	1361-1365
Number of pages	5
Journal	SYNLETT
Volume	9
Publication status	Published - 2008

Keywords

organometallic reagents
lithiation
amino alcohols
microreactors
nucleophilic addition

Cite this

@article{37044a1bb9ea4535ad4bc36ffa5576ff,

title = "Butyllithium-mediated coupling of aryl bromides with ketones under in-situ-quench (ISQ) conditions: an efficient one-step protocol applicable to microreactor technology",

keywords = "organometallic reagents, lithiation, amino alcohols, microreactors, nucleophilic addition",

author = "Sachio Goto and Janna Velder and {El Sheikh}, Sherif and Yuki Sakamoto and Masatoshi Mitani and Sait Elmas and Andreas Adler and Anne Becker and J{\"o}rg-Martin Neud{\"o}rfl and Johann Lex and Hans-G{\"u}nther Schmalz",

year = "2008",

language = "English",

volume = "9",

pages = "1361--1365",

journal = "SYNLETT",

issn = "0936-5214",

publisher = "Georg Thieme Verlag KG",

}

TY - JOUR

T1 - Butyllithium-mediated coupling of aryl bromides with ketones under in-situ-quench (ISQ) conditions

T2 - an efficient one-step protocol applicable to microreactor technology

AU - Goto, Sachio

AU - Velder, Janna

AU - El Sheikh, Sherif

AU - Sakamoto, Yuki

AU - Mitani, Masatoshi

AU - Elmas, Sait

AU - Adler, Andreas

AU - Becker, Anne

AU - Neudörfl, Jörg-Martin

AU - Lex, Johann

AU - Schmalz, Hans-Günther

PY - 2008

Y1 - 2008

KW - organometallic reagents

KW - lithiation

KW - amino alcohols

KW - microreactors

KW - nucleophilic addition

M3 - Article

SN - 0936-5214

VL - 9

SP - 1361

EP - 1365

JO - SYNLETT

JF - SYNLETT

ER -