C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Andrew Epstein; Jonathan Gleadle; Luke McNeill; Kirsty Hewitson; John O'Rourke; David Mole; Mridul Mukherji; Eric Metzen; Michael Wilson; Anu Dhanda; Ya-Min Tian; Norma Masson; Donald Hamilton; Panu Jaakkola; Robert Barstead; Jonathan Hodgkin; Patrick Maxwell; Christopher Pugh; Christopher Schofield; Peter Ratcliffe

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Andrew Epstein, Jonathan Gleadle, Luke McNeill, Kirsty Hewitson, John O'Rourke, David Mole, Mridul Mukherji, Eric Metzen, Michael Wilson, Anu Dhanda, Ya-Min Tian, Norma Masson, Donald Hamilton, Panu Jaakkola, Robert Barstead, Jonathan Hodgkin, Patrick Maxwell, Christopher Pugh, Christopher Schofield, Peter Ratcliffe

Research output: Contribution to journal › Article › peer-review

2925 Citations (Scopus)

Original language	English
Pages (from-to)	43-54
Number of pages	12
Journal	Cell
Volume	107
Issue number	1
Publication status	Published - 2001

Cite this

Epstein, A., Gleadle, J., McNeill, L., Hewitson, K., O'Rourke, J., Mole, D., Mukherji, M., Metzen, E., Wilson, M., Dhanda, A., Tian, Y.-M., Masson, N., Hamilton, D., Jaakkola, P., Barstead, R., Hodgkin, J., Maxwell, P., Pugh, C., Schofield, C., & Ratcliffe, P. (2001). C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell, 107(1), 43-54.

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title = "C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation",

author = "Andrew Epstein and Jonathan Gleadle and Luke McNeill and Kirsty Hewitson and John O'Rourke and David Mole and Mridul Mukherji and Eric Metzen and Michael Wilson and Anu Dhanda and Ya-Min Tian and Norma Masson and Donald Hamilton and Panu Jaakkola and Robert Barstead and Jonathan Hodgkin and Patrick Maxwell and Christopher Pugh and Christopher Schofield and Peter Ratcliffe",

year = "2001",

language = "English",

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Epstein, A, Gleadle, J, McNeill, L, Hewitson, K, O'Rourke, J, Mole, D, Mukherji, M, Metzen, E, Wilson, M, Dhanda, A, Tian, Y-M, Masson, N, Hamilton, D, Jaakkola, P, Barstead, R, Hodgkin, J, Maxwell, P, Pugh, C, Schofield, C & Ratcliffe, P 2001, 'C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation', Cell, vol. 107, no. 1, pp. 43-54.

TY - JOUR

T1 - C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

AU - Epstein, Andrew

AU - Gleadle, Jonathan

AU - McNeill, Luke

AU - Hewitson, Kirsty

AU - O'Rourke, John

AU - Mole, David

AU - Mukherji, Mridul

AU - Metzen, Eric

AU - Wilson, Michael

AU - Dhanda, Anu

AU - Tian, Ya-Min

AU - Masson, Norma

AU - Hamilton, Donald

AU - Jaakkola, Panu

AU - Barstead, Robert

AU - Hodgkin, Jonathan

AU - Maxwell, Patrick

AU - Pugh, Christopher

AU - Schofield, Christopher

AU - Ratcliffe, Peter

PY - 2001

Y1 - 2001

M3 - Article

SN - 0092-8674

VL - 107

SP - 43

EP - 54

JO - Cell

JF - Cell

IS - 1

ER -