Calcium distributions in human hair by ToF-SIMS

I. M. Kempson; W. M. Skinner; P. K. Kirkbride

doi:10.1016/j.bbagen.2003.09.003

Calcium distributions in human hair by ToF-SIMS

I. M. Kempson, W. M. Skinner, P. K. Kirkbride

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Calcium distributions on internal and external surfaces of longitudinally sectioned hairs were analysed with Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS). Externally, calcium deposits were observed at the cuticle scale edges. Internal sections showed that the bulk of calcium exists within or just inside the cuticle layer. The medulla may or may not be enriched and other localised concentrations exist in one of two forms; either associated with granular structures or the hair proteins. Calcium appears to show an affinity for proteins with low sulfur content.

Original language	English
Pages (from-to)	1-5
Number of pages	5
Journal	Biochimica et Biophysica Acta - General Subjects
Volume	1624
Issue number	1-3
DOIs	https://doi.org/10.1016/j.bbagen.2003.09.003
Publication status	Published - 5 Dec 2003
Externally published	Yes

Keywords

Localisation
Melanin
Protein
Section
SEM-EDX

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AU - Skinner, W. M.

AU - Kirkbride, P. K.

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AB - Calcium distributions on internal and external surfaces of longitudinally sectioned hairs were analysed with Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS). Externally, calcium deposits were observed at the cuticle scale edges. Internal sections showed that the bulk of calcium exists within or just inside the cuticle layer. The medulla may or may not be enriched and other localised concentrations exist in one of two forms; either associated with granular structures or the hair proteins. Calcium appears to show an affinity for proteins with low sulfur content.

KW - Localisation

KW - Melanin

KW - Protein

KW - Section

KW - SEM-EDX

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