Can targeted intervention in CRC patients'relatives influence screening behaviour? A pilot study

J. H. Stephens, J. W. E. Moore

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


Objective: This study aimed to assess the utility of a standardised risk information tool with respect to the uptake of screening activities administered to an accessible population of first-degree relatives of patients with sporadic colorectal cancer. Method: Patients admitted for colorectal cancer resection were invited to enrol their family unit in the study. Families were randomised either to receive standard care or the intervention tool. The intervention group received a structured one page pamphlet outlining the risk associated with a family history of colorectal cancer, and the availability of and potential benefits from screening. Three months after the initial contact with the index patient, family members were invited to participate in a telephone interview. Primary end-points were both intention to screen and uptake of screening activities. Results: Forty-seven families had 156 eligible first degree relatives. Ninety-one consented to participate and were enrolled: 59 received standard care, 32 received the intervention. Age and sex were similar between groups. There was no significant difference in previous screening activities. The intervention tool had no influence on perceived self-risk of developing colorectal cancer or uptake of screening activities within the study period. Conclusion: This study suggests that the provision of targeted risk information to first-degree relatives is not likely to positively influence screening behaviour. Health care providers need to find alternative methods of disseminating information to this high-risk group.

Original languageEnglish
Pages (from-to)179-186
Number of pages8
JournalColorectal Disease
Issue number2
Publication statusPublished - Feb 2008
Externally publishedYes


  • Colorectal neoplasms
  • First-degree relative
  • Screening


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