Cannabinoids for sleep disorders: Weeding through the evidence

Sleep disorders are common and include obstructive sleep apnoea (OSA), insomnia, parasomnias, movement disorders and neurological disorders such as narcolepsy. Consequences of untreated sleep disorders include cardiovascular disease, metabolic dysfunction, cognitive impairment and depression. The financial burden of sleep disorders is also significant with the total annual cost of undiagnosed OSA in the US alone estimated to be in excess of US$149b in 2015 [1]. It is estimated that US$100b per year would be saved if every adult with OSA in the US were diagnosed and treated.