Case report: Severe congenital malaria acquired in utero

Jeanne Poespoprodjo, Afdal hasanuddin, Wendy Fobia, Paulus Sugiarto, E Kenangalem, Daniel Lampah, E Tjitra, Ric Price, Nicholas Anstey

    Research output: Contribution to journalArticlepeer-review

    19 Citations (Scopus)

    Abstract

    Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptom-atic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects.

    Original languageEnglish
    Pages (from-to)563-565
    Number of pages3
    JournalAmerican Journal of Tropical Medicine and Hygiene
    Volume82
    Issue number4
    DOIs
    Publication statusPublished - Apr 2010

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