Case report: Severe congenital malaria acquired in utero

Jeanne Poespoprodjo; Afdal hasanuddin; Wendy Fobia; Paulus Sugiarto; E Kenangalem; Daniel Lampah; E Tjitra; Ric Price; Nicholas Anstey

doi:10.4269/ajtmh.2010.09-0744

Case report: Severe congenital malaria acquired in utero

Jeanne Poespoprodjo
, Afdal hasanuddin
, Wendy Fobia
, Paulus Sugiarto
, E Kenangalem
, Daniel Lampah
, E Tjitra
, Ric Price
, Nicholas Anstey

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptom-atic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects.

Original language	English
Pages (from-to)	563-565
Number of pages	3
Journal	American Journal of Tropical Medicine and Hygiene
Volume	82
Issue number	4
DOIs	https://doi.org/10.4269/ajtmh.2010.09-0744
Publication status	Published - Apr 2010

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SDG 3 Good Health and Well-being

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10.4269/ajtmh.2010.09-0744

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title = "Case report: Severe congenital malaria acquired in utero",

abstract = "Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptom-atic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects.",

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T1 - Case report: Severe congenital malaria acquired in utero

AU - Poespoprodjo, Jeanne

AU - hasanuddin, Afdal

AU - Fobia, Wendy

AU - Sugiarto, Paulus

AU - Kenangalem, E

AU - Lampah, Daniel

AU - Tjitra, E

AU - Price, Ric

AU - Anstey, Nicholas

PY - 2010/4

Y1 - 2010/4

N2 - Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptom-atic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects.

AB - Vertical transmission of Plasmodium falciparum is under-recognized and usually associated with asymptom-atic low-level parasitemia at birth. We report symptomatic congenital malaria presenting as a neonatal sepsis syndrome. The presence at birth of a high asexual parasitemia, gametocytemia, and splenomegaly indicated in utero rather than intrapartum transmission. The neonate was successfully treated with intravenous artesunate followed by oral dihydroartemisinin-piperaquine, without apparent adverse effects.

UR - https://www.scopus.com/pages/publications/77950937335

U2 - 10.4269/ajtmh.2010.09-0744

DO - 10.4269/ajtmh.2010.09-0744

M3 - Article

SN - 0002-9637

VL - 82

SP - 563

EP - 565

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

IS - 4

ER -

Case report: Severe congenital malaria acquired in utero

Abstract

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