Central sleep apnoea

D G McSharry, D J Eckert, A Malhotra

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Central sleep apnoea (CSA) encompasses a diverse group of conditions from periodic breathing at altitude to opiate-induced CSA. Considerable overlap exists between obstructive sleep apnoea and CSA in terms of pathogenesis and pathophysiology. CSA syndromes can be broadly classified into patients with high drive and those with low drive. Many forms of CSA can ultimately lead to adverse cardiovascular outcomes. Treatment can be challenging and varies according to the underlying aetiology of the CSA. Some exciting new therapeutic options (e.g. phasic administration of CO2) require further research, in particular with respect to safety and potential outcome benefits.
Original languageEnglish
Title of host publicationSleep apnoea
EditorsW T McNicholas, M R Bonsignore
PublisherEuropean Respiratory Society
Number of pages15
ISBN (Print)9781849840071
Publication statusPublished - 1 Dec 2010

Publication series

NameEuropean Respiratory Society monograph
Publisher: European Respiratory Society


  • sleep disorders
  • sleep apnoea
  • Breath analysis


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