Challenges of calculating cost-effectiveness thresholds

Laura Vallejo-Torres, Karl Claxton, Laura C. Edney, Jonathan Karnon, James Lomas, Jessica Ochalek, Mike Paulden, Niek Stadhouders, David J. Vanness

Research output: Contribution to journalLetterpeer-review

1 Citation (Scopus)
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Health systems around the globe use cost-effectiveness analysis to support health funding decisions. Cost-effectiveness analysis compares benefits associated with new technologies with benefits necessarily forsaken when resources are displaced to pay for the new technologies. Systems aiming to improve the health of their populations but facing a budget constraint should use cost-effectiveness thresholds (CETs) that reflect the health opportunity costs of funding decisions.

In their Article (June, 2023), Andres Pichon-Riviere and colleagues derive CETs based on aspirational targets on the growth in life expectancy and on the growth in health expenditure...
Original languageEnglish
Pages (from-to)e1508
Number of pages1
JournalThe Lancet Global Health
Issue number10
Early online date19 Sept 2023
Publication statusPublished - Oct 2023


  • Health systems
  • Health funding
  • Cost-effectiveness analysis
  • Population health


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