Changes in the Second Ventilatory Threshold Following Individualised versus Standardised Exercise Prescription among Physically Inactive Adults: A Randomised Trial

The second ventilatory threshold (VT₂) is established as an important indicator of exercise intensity tolerance. A higher VT₂ allows for greater duration of higher intensity exercise participation and subsequently greater reductions in cardiovascular disease (CVD) risk. This study aimed to com-pare the efficacy of standardised and individualised exercise prescription on VT₂ among physically inactive adults. Forty-nine physically inactive male and female participants (48.6 ± 11.5 years) were recruited and randomised into a 12-week standardised (n = 25) or individualised (n = 24) exercise prescription intervention. The exercise intensity for the standardised and individualised groups was prescribed as a percentage of heart rate reserve (HRR) or relative to the first ventilatory threshold (VT₁) and VT₂, respectively. Participants were required to complete a maximal graded exercise test at pre-and post-intervention to determine VT₁ and VT₂. Participants were categorised as responders to the intervention if an absolute VT₂ change of at least 1.9% was attained. Thirty-eight participants were included in the analysis. A significant difference in VT₂ change was found between individualised (pre vs. post: 70.6% vs. 78.7% maximum oxygen uptake (VO₂ max)) and standardised (pre vs. post: 72.5% vs. 72.3% VO₂ max) exercise groups. Individualised exercise prescription was significantly more efficacious (p = 0.04) in eliciting a positive response in VT₂ (15/19, 79%) when compared to the standardised exercise group (9/19, 47%). Individualised exercise prescription appears to be more efficacious than standardised exercise prescription in eliciting a positive VT₂ change among physically inactive adults. Increasing VT₂ allows for greater tolerance to higher exercise intensities and therefore greater cardiovascular health outcomes.