Characterisation of novel and rare Y-chromosome short tandem repeat alleles in self-declared South Australian Aboriginal database

Tegan Collins, Renee Ottens, Kaye Ballantyne, Nano Nagle, Julianne Henry, Duncan Taylor, Michael Gardner, Alison Fitch, Amanda Goodman, Roland van Oorschot, R. Mitchell, Adrian Linacre

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    Y-chromosome short tandem repeats (Y-STRs) are used in forensic science laboratories all over the world, as their application is wide and often vital in solving casework. Analysis of an in-house database of South Australian self-declared Aboriginal males held by Forensic Science South Australia (FSSA) using the Applied Biosystem's AmpFℓSTR® Yfiler™ PCR Amplification Kit revealed 43 variant Y-STR alleles at 6 of the 17 loci. All variant alleles were sequenced to determine the exact repeat structure for each. As a high level of admixture has previously been found within the SA Aboriginal database, samples were haplogrouped using Y-SNPs to determine their likely geographical origin. Although a number of variant alleles were associated with non-Aboriginal Y-haplogroups, a high frequency was observed within the Australian K-M9 lineage. Detailed knowledge of these variant alleles may have further application in the development of new DNA markers for identification purposes, and in population and evolutionary studies of Australian Aborigines.

    Original languageEnglish
    Pages (from-to)27-31
    Number of pages5
    JournalInternational Journal of Legal Medicine
    Volume128
    Issue number1
    DOIs
    Publication statusE-pub ahead of print - 2014

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