Characterization of a novel carbonic anhydrase from freshwater pearl mussel Hyriopsis cumingii and the expression profile of its transcript in response to environmental conditions

Gang Ren, Yan Wang, Jianguang Qin, Jinyu Tang, Xiaofei Zheng, Youming Li

    Research output: Contribution to journalArticlepeer-review

    13 Citations (Scopus)

    Abstract

    Gene encoding for α-carbonic anhydrases (α-CAs) and their functions in fundamental metabolism and biomineralization are widely identified in mollusks. However, the transcriptional regulation of α-CA genes in response to various environmental conditions remains unknown. In the present study, we characterized a cDNA encoding for an α-CA (HcCA) from the freshwater pearl mussel Hyriopsis cumingii. The spatial and temporal expression patterns of HcCA indicate that this gene is mainly expressed in the mantle of juvenile mussels. The expression profile of HcCA under various environmental conditions reveals that the transcription of HcCA is significantly regulated by Ca2+ concentration, water temperature, pH and air exposure. Our results suggest that HcCA is a crucial target gene by which the external environmental conditions affecting shell growth and pH homeostasis of H. cumingii. 2014 Elsevier B.V.

    Original languageEnglish
    Pages (from-to)56-62
    Number of pages7
    JournalGene
    Volume546
    Issue number1
    DOIs
    Publication statusPublished - 1 Aug 2014

    Keywords

    • Carbonic anhydrase
    • Expression
    • Hyriopsis cumingii
    • PH homeostasis
    • Shell growth

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