@article{929a0ddaf581496a92f79d2d4a976d2c,
title = "Chronic kidney disease and valvular heart disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference",
abstract = "Chronic kidney disease (CKD) is a major risk factor for valvular heart disease (VHD). Mitral annular and aortic valve calcifications are highly prevalent in CKD patients and commonly lead to valvular stenosis and regurgitation, as well as complications including conduction system abnormalities and endocarditis. VHD, especially mitral regurgitation and aortic stenosis, is associated with significantly reduced survival among CKD patients. Knowledge related to VHD in the general population is not always applicable to CKD patients because the pathophysiology may be different, and CKD patients have a high prevalence of comorbid conditions and elevated risk for periprocedural complications and mortality. This Kidney Disease: Improving Global Outcomes (KDIGO) review of CKD and VHD seeks to improve understanding of the epidemiology, pathophysiology, diagnosis, and treatment of VHD in CKD by summarizing knowledge gaps, areas of controversy, and priorities for research.",
keywords = "aortic stenosis, chronic kidney disease, end-stage kidney disease, mitral annular calcification, valvular heart disease",
author = "Marwick, {Thomas H.} and Kerstin Amann and Sripal Bangalore and Cavalcante, {Jo{\~a}o L.} and Charytan, {David M.} and Craig, {Jonathan C.} and Gill, {John S.} and Hlatky, {Mark A.} and Jardine, {Alan G.} and Ulf Landmesser and Newby, {L. Kristin} and Herzog, {Charles A.} and Michael Cheung and Wheeler, {David C.} and Winkelmayer, {Wolfgang C.} and Sarnak, {Mark J.} and {Conference Participants} and Debasish Banerjee and Carlo Briguori and Chang, {Tara I.} and Chen, {Chien Liang} and deFilippi, {Christopher R.} and Xiaoqiang Ding and Ferro, {Charles J.} and Jagbir Gill and Mario G{\"o}ssl and Isbel, {Nicole M.} and Hideki Ishii and Jardine, {Meg J.} and Kalra, {Philip A.} and G{\"u}nther Laufer and Lentine, {Krista L.} and Lobdell, {Kevin W.} and Lok, {Charmaine E.} and London, {G{\'e}rard M.} and Jolanta Ma{\l}yszko and Mark, {Patrick B.} and Mohamed Marwan and Yuxin Nie and Parfrey, {Patrick S.} and Roberto Pecoits-Filho and Helen Pilmore and Qunibi, {Wajeh Y.} and Paolo Raggi and Marcello Rattazzi and Patrick Rossignol and Josiah Ruturi and Charumathi Sabanayagam and Shanahan, {Catherine M.} and Shroff, {Gautam R.} and Rukshana Shroff and Webster, {Angela C.} and Weiner, {Daniel E.} and Simon Winther and Wiseman, {Alexander C.} and Anthony Yip and Alexander Zarbock",
year = "2019",
month = oct,
day = "1",
doi = "10.1016/j.kint.2019.06.025",
language = "English",
volume = "96",
pages = "836--849",
journal = "Kidney International",
issn = "0085-2538",
publisher = "Kidney International",
number = "4",
}