Abstract
We describe three patients with RA who developed cirrhosis while taking low dose methotrexate (MTX). This report includes a review of the risk factors for cirrhosis occurring in association with MTX. Two of these patients were part of a prospective study to quantify changes in pericellular and total collagen in 76 patients with RA receiving low dose pulse MTX, giving a point prevalence of cirrhosis of 2.63%.
Original language | English |
---|---|
Pages (from-to) | 981-984 |
Number of pages | 4 |
Journal | Rheumatology |
Volume | 33 |
Issue number | 10 |
DOIs | |
Publication status | Published - Oct 1994 |
Keywords
- Cirrhosis
- Liver biopsy
- Methotrexate
- Rheumatoid arthritis