Cirrhosis in patients with rheumatoid arthritis receiving low dose methotrexate

G. Chandran, M. J. Ahern, Pauline De la M. Hall , R. Geddes, M. D. Smith, W. Hill, J. H. Harley

    Research output: Contribution to journalArticlepeer-review

    16 Citations (Scopus)


    We describe three patients with RA who developed cirrhosis while taking low dose methotrexate (MTX). This report includes a review of the risk factors for cirrhosis occurring in association with MTX. Two of these patients were part of a prospective study to quantify changes in pericellular and total collagen in 76 patients with RA receiving low dose pulse MTX, giving a point prevalence of cirrhosis of 2.63%.

    Original languageEnglish
    Pages (from-to)981-984
    Number of pages4
    Issue number10
    Publication statusPublished - Oct 1994


    • Cirrhosis
    • Liver biopsy
    • Methotrexate
    • Rheumatoid arthritis


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