Cirrhosis in patients with rheumatoid arthritis receiving low dose methotrexate

G. Chandran, M. J. Ahern, Pauline De la M. Hall , R. Geddes, M. D. Smith, W. Hill, J. H. Harley

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    Abstract

    We describe three patients with RA who developed cirrhosis while taking low dose methotrexate (MTX). This report includes a review of the risk factors for cirrhosis occurring in association with MTX. Two of these patients were part of a prospective study to quantify changes in pericellular and total collagen in 76 patients with RA receiving low dose pulse MTX, giving a point prevalence of cirrhosis of 2.63%.

    Original languageEnglish
    Pages (from-to)981-984
    Number of pages4
    JournalRheumatology
    Volume33
    Issue number10
    DOIs
    Publication statusPublished - Oct 1994

    Keywords

    • Cirrhosis
    • Liver biopsy
    • Methotrexate
    • Rheumatoid arthritis

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    Chandran, G., Ahern, M. J., De la M. Hall , P., Geddes, R., Smith, M. D., Hill, W., & Harley, J. H. (1994). Cirrhosis in patients with rheumatoid arthritis receiving low dose methotrexate. Rheumatology, 33(10), 981-984. https://doi.org/10.1093/rheumatology/33.10.981