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Cirrhosis in patients with rheumatoid arthritis receiving low dose methotrexate

  • G. Chandran
  • , M. J. Ahern
  • , Pauline De la M. Hall
  • , R. Geddes
  • , M. D. Smith
  • , W. Hill
  • , J. H. Harley

    Research output: Contribution to journalArticlepeer-review

    16 Citations (Scopus)

    Abstract

    We describe three patients with RA who developed cirrhosis while taking low dose methotrexate (MTX). This report includes a review of the risk factors for cirrhosis occurring in association with MTX. Two of these patients were part of a prospective study to quantify changes in pericellular and total collagen in 76 patients with RA receiving low dose pulse MTX, giving a point prevalence of cirrhosis of 2.63%.

    Original languageEnglish
    Pages (from-to)981-984
    Number of pages4
    JournalRheumatology
    Volume33
    Issue number10
    DOIs
    Publication statusPublished - Oct 1994

    Keywords

    • Cirrhosis
    • Liver biopsy
    • Methotrexate
    • Rheumatoid arthritis

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