Clinical aspects of sphincter of Oddi function and dysfunction

J. Toouli, A. Craig

Research output: Contribution to journalReview articlepeer-review

20 Citations (Scopus)


The sphincter of Oddi (SO) functions to regulate the flow of bile and pancreatic juices as well as to prevent the reflux of duodenal contents into the pancreatobiliary system. When dysfunction of the sphincter occurs, symptoms develop relating to either the biliary or pancreatic portions of the sphincter. The mechanism of this dysfunction remains speculative. SO manometry remains the "gold standard" to correctly diagnose the disorder and stratify therapy. Division of the sphincter is effective for SO stenosis, but there is no proven therapy for SO dyskinesia.

Original languageEnglish
Pages (from-to)116-122
Number of pages7
JournalCurrent Gastroenterology Reports
Issue number2
Publication statusPublished - Apr 1999
Externally publishedYes


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