Clinical pharmacology of GP53,633-a new non-steroidal anti-inflammatory drug - in patients with rheumatoid arthritis

S. Wanwimolruk, D. Thomas, D. J. Birkett, J. O. Miners, P. M. Brooks

    Research output: Contribution to journalReview article

    Abstract

    GP53,633 is a new basic non-steroidal anti-inflammatory drug showing analgesic and anti-inflammatory activity in animal models. Pharmacokinetic studies in 6 patients with rheumatoid arthritis show it to be rapidly absorbed with a short half life (approximately 2 hours). No change in pharmacokinetics is seen over a two week treatment period. Clinical parameters of inflammation were reduced and no adverse reactions were seen.

    Original languageEnglish
    Pages (from-to)424-427
    Number of pages4
    JournalAgents and Actions
    Volume15
    Issue number3-4
    DOIs
    Publication statusPublished - 1 Oct 1984

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