Clinical pharmacology of GP53,633-a new non-steroidal anti-inflammatory drug - in patients with rheumatoid arthritis

S. Wanwimolruk; D. Thomas; D. J. Birkett; J. O. Miners; P. M. Brooks

doi:10.1007/BF01972382

Clinical pharmacology of GP53,633-a new non-steroidal anti-inflammatory drug - in patients with rheumatoid arthritis

S. Wanwimolruk, D. Thomas, D. J. Birkett, J. O. Miners, P. M. Brooks

Research output: Contribution to journal › Review article › peer-review

Abstract

GP53,633 is a new basic non-steroidal anti-inflammatory drug showing analgesic and anti-inflammatory activity in animal models. Pharmacokinetic studies in 6 patients with rheumatoid arthritis show it to be rapidly absorbed with a short half life (approximately 2 hours). No change in pharmacokinetics is seen over a two week treatment period. Clinical parameters of inflammation were reduced and no adverse reactions were seen.

Original language	English
Pages (from-to)	424-427
Number of pages	4
Journal	Agents and Actions
Volume	15
Issue number	3-4
DOIs	https://doi.org/10.1007/BF01972382
Publication status	Published - 1 Oct 1984

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abstract = "GP53,633 is a new basic non-steroidal anti-inflammatory drug showing analgesic and anti-inflammatory activity in animal models. Pharmacokinetic studies in 6 patients with rheumatoid arthritis show it to be rapidly absorbed with a short half life (approximately 2 hours). No change in pharmacokinetics is seen over a two week treatment period. Clinical parameters of inflammation were reduced and no adverse reactions were seen.",

author = "S. Wanwimolruk and D. Thomas and Birkett, {D. J.} and Miners, {J. O.} and Brooks, {P. M.}",

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AU - Miners, J. O.

AU - Brooks, P. M.

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AB - GP53,633 is a new basic non-steroidal anti-inflammatory drug showing analgesic and anti-inflammatory activity in animal models. Pharmacokinetic studies in 6 patients with rheumatoid arthritis show it to be rapidly absorbed with a short half life (approximately 2 hours). No change in pharmacokinetics is seen over a two week treatment period. Clinical parameters of inflammation were reduced and no adverse reactions were seen.

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Clinical pharmacology of GP53,633-a new non-steroidal anti-inflammatory drug - in patients with rheumatoid arthritis

Abstract

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