Clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome

Amita Ingole; Tarun Bastiampillai; Prashant Tibrewal

doi:10.1016/j.ajp.2017.08.009

Clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome

Amita Ingole, Tarun Bastiampillai, Prashant Tibrewal

Research output: Contribution to journal › Letter › peer-review

13 Citations (Scopus)

Abstract

Clozapine withdrawal psychosis is a relatively well-recognised phenomenon. However, literature exploring clozapine withdrawal associated catatonia is limited to a few case reports (Bastiampillai et al., 2009). We present a case of clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome (NMS) and discuss its clinical implications.

A better understanding of clozapine withdrawal catatonia and psychosis may also allow us to better analyse the unique properties of clozapine, with possible suggestion that it could be a GABA agent further supporting the importance of the GABA system in schizophrenia (O’Connor and O’Shea, 2015).

Original language	English
Pages (from-to)	96-97
Number of pages	2
Journal	Asian Journal of Psychiatry
Volume	30
Early online date	12 Aug 2017
DOIs	https://doi.org/10.1016/j.ajp.2017.08.009
Publication status	Published - Dec 2017

Keywords

Clozapine
Withdrawal
Catatonia
Psychosis
Neuroleptic Malignant Syndrome

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title = "Clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome",

abstract = "Clozapine withdrawal psychosis is a relatively well-recognised phenomenon. However, literature exploring clozapine withdrawal associated catatonia is limited to a few case reports (Bastiampillai et al., 2009). We present a case of clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome (NMS) and discuss its clinical implications.A better understanding of clozapine withdrawal catatonia and psychosis may also allow us to better analyse the unique properties of clozapine, with possible suggestion that it could be a GABA agent further supporting the importance of the GABA system in schizophrenia (O{\textquoteright}Connor and O{\textquoteright}Shea, 2015).",

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T1 - Clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome

AU - Ingole, Amita

AU - Bastiampillai, Tarun

AU - Tibrewal, Prashant

PY - 2017/12

Y1 - 2017/12

N2 - Clozapine withdrawal psychosis is a relatively well-recognised phenomenon. However, literature exploring clozapine withdrawal associated catatonia is limited to a few case reports (Bastiampillai et al., 2009). We present a case of clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome (NMS) and discuss its clinical implications.A better understanding of clozapine withdrawal catatonia and psychosis may also allow us to better analyse the unique properties of clozapine, with possible suggestion that it could be a GABA agent further supporting the importance of the GABA system in schizophrenia (O’Connor and O’Shea, 2015).

AB - Clozapine withdrawal psychosis is a relatively well-recognised phenomenon. However, literature exploring clozapine withdrawal associated catatonia is limited to a few case reports (Bastiampillai et al., 2009). We present a case of clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome (NMS) and discuss its clinical implications.A better understanding of clozapine withdrawal catatonia and psychosis may also allow us to better analyse the unique properties of clozapine, with possible suggestion that it could be a GABA agent further supporting the importance of the GABA system in schizophrenia (O’Connor and O’Shea, 2015).

KW - Clozapine

KW - Withdrawal

KW - Catatonia

KW - Psychosis

KW - Neuroleptic Malignant Syndrome

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DO - 10.1016/j.ajp.2017.08.009

M3 - Letter

SN - 1876-2018

VL - 30

SP - 96

EP - 97

JO - Asian Journal of Psychiatry

JF - Asian Journal of Psychiatry

ER -

Clozapine withdrawal catatonia, psychosis and associated neuroleptic malignant syndrome

Abstract

Keywords

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