TY - JOUR
T1 - Clozapine withdrawal malignant catatonia in a medical intensive care unit setting
AU - Brailey, Jonathan
AU - Bastiampillai, Tarun
PY - 2020/8
Y1 - 2020/8
N2 - Catatonia is a psychomotor syndrome associated with several psychiatric and medical conditions, and is thought to be related to GABA hypofunction (Lander et al., 2018; Walther et al., 2019). Estimates of the prevalence of catatonia range from 9 to 18 % in acutely ill psychiatric inpatients (Lander et al., 2018). Abrupt cessation of clozapine is known to frequently cause an exacerbation of psychotic symptoms as well as delirium, nausea and diarrhoea, and is less commonly associated with neuroleptic malignant syndrome (NMS) and catatonia (Moncrieff, 2006; Okada and Yasuda JKM, 2020; Vellekkatt et al., 2019). We present a case of clozapine withdrawal malignant catatonia occurring whilst in a medical intensivecare unit (ICU)...
AB - Catatonia is a psychomotor syndrome associated with several psychiatric and medical conditions, and is thought to be related to GABA hypofunction (Lander et al., 2018; Walther et al., 2019). Estimates of the prevalence of catatonia range from 9 to 18 % in acutely ill psychiatric inpatients (Lander et al., 2018). Abrupt cessation of clozapine is known to frequently cause an exacerbation of psychotic symptoms as well as delirium, nausea and diarrhoea, and is less commonly associated with neuroleptic malignant syndrome (NMS) and catatonia (Moncrieff, 2006; Okada and Yasuda JKM, 2020; Vellekkatt et al., 2019). We present a case of clozapine withdrawal malignant catatonia occurring whilst in a medical intensivecare unit (ICU)...
KW - Catatonia
KW - Clozapine withdrawal
UR - http://www.scopus.com/inward/record.url?scp=85083286882&partnerID=8YFLogxK
U2 - 10.1016/j.ajp.2020.102043
DO - 10.1016/j.ajp.2020.102043
M3 - Letter
AN - SCOPUS:85083286882
SN - 1876-2018
VL - 52
JO - Asian Journal of Psychiatry
JF - Asian Journal of Psychiatry
M1 - 102043
ER -
