Abstract
Background Hypertension is a major risk factor for stroke, coronary artery disease and kidney damage in adults. There is a paucity of data on the long-term sequelae of persistent hypertension in children, but it is known that children with hypertension have evidence of end-organ damage and are at risk of hypertension into adulthood. The prevalence of hypertension in children is increasing, most likely owing to a concurrent rise in obesity. In children with hypertension, nonpharmacological measures are often recommended as first-line therapy, but a significant proportion of children will eventually require pharmacological treatment to reduce blood pressure, especially those with evidence of end-organ damage at presentation or during follow-up. A systematic review of the effects of antihypertensive agents in children has not previously been conducted.
Original language | English |
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Pages (from-to) | 581-583 |
Number of pages | 3 |
Journal | Evidence-Based Child Health |
Volume | 9 |
Issue number | 3 |
DOIs | |
Publication status | Published - 19 Sep 2014 |
Externally published | Yes |
Keywords
- hypertension
- paediatric
- clinical trials
- medications
- drugs
- drugsmeta-analysis