Cochrane review summary: Oxycodone or Oxycodone plus paracetamol for acute postoperative pain in adults

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Abstract

In this short communication we wanted to summarise a Cochrane review that investigated the analgesic effect of single dose oral oxycodone, with or without the addition of paracetamol, for adults with postoperative pain. Oxycodone at doses of 5mg and above is an effective analgesia for patients with moderate to severe postoperative pain. The efficacy of oxycodone is increased with the addition of paracetamol. The use of oxycodone 10mg plus paracetamol 625mg can be considered for use in the pain relief protocol in post-operative settings. Clinicians should consider a range of factors before prescribing or administering oxycodone for acute post-operative pain, including but not limited to, individual patient clinical profile, adverse effects, cost and patient preference.

Original languageEnglish
Pages (from-to)439-441
Number of pages3
JournalJournal of Pain Management
Volume4
Issue number4
Publication statusPublished - 2011
Externally publishedYes

Keywords

  • Analgesia
  • Oxycodone
  • Paracetamol
  • Post-operative pain
  • Systematic review

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