Colonic dysmotility in constipation

Philip Dinning, Carlo Di Lorenzo

    Research output: Contribution to journalArticlepeer-review

    67 Citations (Scopus)


    Constipation is a common and distressing condition with major morbidity, health care burden, and impact on quality of life. Colonic motor dysfunction remains the leading hypothesis to explain symptom generation in the most severe cases of chronic constipation and physiological testing plays a role in identifying the colonic dysmotility and the subsequent patient management. Measurement of colonic motor patterns and transit has enhanced our knowledge of normal and abnormal colonic motor physiology. The scope of this review encompasses the latest findings that improve our understanding of the motility disorders associated with colonic dysfunction in both the paediatric and adult population suffering from constipation.

    Original languageEnglish
    Pages (from-to)89-101
    Number of pages13
    JournalBest Practice and Research in Clinical Gastroenterology
    Issue number1
    Publication statusPublished - Feb 2011


    • Adult
    • Colon
    • Colon transit
    • Constipation
    • Manometry
    • Paediatric


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