Communication Within Animal Cells

    Research output: Book/ReportBookpeer-review

    Abstract

    The ordered growth and functioning of animal cells requires the transfer of information from one part of the cell to another. This information comes from a bewildering variety of sources, both within and outside the cell. Hormones, neurotransmitters, growth factors and extracellular metabolites interact with specific receptors on the plasma membrane or in the cytoplasm. Inside the cell, information is relayed by intracellular messengers, including cyclic nucleotides, inositol polyphosphates, diacylglycerol and calcium, and by GTP-binding proteins, protein kinases, and DNA-binding proteins. Finely balanced interactions between these different signalling pathways ensure that the required response occurs, and abnormalities in any of the components of the system can lead to a variety of diseases, including cancer. This textbook brings together and puts into perspective a large body of knowledge about intracellular
    Original languageEnglish
    Place of PublicationUK
    PublisherOxford University Press
    Number of pages360
    ISBN (Print)9780198547266
    Publication statusPublished - 4 Jun 1992

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